Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | MPL | P40238 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.38 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.38 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.38 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.38 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4828428 | 0.79 | ALOX15 (0.55) | NPC1RAB9AL3MBTL1GAASMN1; SMN2 | |
| SCHEMBL20385737 | 0.77 | ENPP3 (0.51) | NPC1MPLNOTUMIDO1RAB9A | |
| SCHEMBL14380708 | 0.74 | ALOX15 (0.40) | GAAALDH1A1 | |
| SCHEMBL20389346 | 0.74 | NPC1 (0.43) | NPC1MPLNOTUMIDO1RAB9A | |
| SCHEMBL14637421 | 0.74 | MPL (0.47) | NPC1MPLNOTUMIDO1RAB9A | |
| SCHEMBL20242216 | 0.74 | MPL (0.51) | NPC1MPLADORA2ANOTUMIDO1 | |
| SCHEMBL20286125 | 0.73 | NPC1 (0.40) | NPC1MPLADORA2AADORA1ADORA3 | |
| SCHEMBL25440347 | 0.73 | CNR2 (0.44) | NPC1MPLADORA2AADORA1ADORA3 | |
| SCHEMBL20385746 | 0.73 | NPC1 (0.40) | NPC1MPLADORA2AADORA1ADORA3 | |
| SCHEMBL10460707 | 0.68 | NPC1 (0.38) | NPC1MPLNOTUMIDO1ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3555100-B1 | BENZODIAZEPINE DERIVATIVES, COMPOSITIONS, AND METHODS FOR TREATING COGNITIVE IMPAIRMENT | AGENEBIO INC (US) | 2023-05-10 | — | — | EP | disclosed |