Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 4/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25442294 | 1.00 | CCR1 (0.53) | CCR1CYP3A4ALDH1A1CTSLCTSB | |
| SCHEMBL25443247 | 0.88 | CCR1 (0.51) | CCR1CYP3A4ALDH1A1CTSLCTSB | |
| SCHEMBL25442295 | 0.88 | CCR1 (0.49) | CCR1ALDH1A1CTSLCTSBCTSK | |
| SCHEMBL25442293 | 0.88 | CCR1 (0.49) | CCR1ALDH1A1CTSLCTSBCTSK | |
| SCHEMBL31117841 | 0.79 | CCR1 (0.47) | CCR1CYP3A4ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL31117778 | 0.79 | CCR1 (0.47) | CCR1CYP3A4ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL28503861 | 0.79 | NPC1 (0.51) | ALDH1A1SMN1; SMN2EPHX1NPC1CYP2C19 | |
| SCHEMBL23903518 | 0.79 | CCR1 (0.53) | CCR1ALDH1A1CTSLCTSBCTSK | |
| SCHEMBL23903522 | 0.79 | CCR1 (0.53) | CCR1ALDH1A1CTSLCTSBCTSK | |
| SCHEMBL25443244 | 0.77 | CCR1 (0.43) | CCR1ALDH1A1EPHX2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230142739-A1 | PROTEIN-PROTEIN INTERACTION STABILIZERS | UNIV CALIFORNIA (US) | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230142739-A1 | PROTEIN-PROTEIN INTERACTION STABILIZERS | HSPBP1, HSPA8, HSPH1 | CCR1 4742/4885CYP3A4 4570/4885ALDH1A1 3889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.