SCHEMBL2544260

SCHEMBL2544260

O=C1C=C(c2cccc3ccccc23)C(=O)N1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.53
KDM4E B2RXH2 2/20 0.49
ALPL P05186 1/20 0.49
GAA P10253 1/20 0.49
PRKD3 O94806 1/20 0.46
PRKCG P05129 1/20 0.46
PRKCB P05771 1/20 0.46
PRKCA P17252 1/20 0.46
PRKCH P24723 1/20 0.46
PRKCI P41743 1/20 0.46
PRKCE Q02156 1/20 0.46
PRKCQ Q04759 1/20 0.46
PRKCZ Q05513 1/20 0.46
PRKCD Q05655 1/20 0.46
PRKD1 Q15139 1/20 0.46
PARP1 P09874 2/20 0.41
TYMP P19971 1/20 0.41
POLB P06746 1/20 0.40
GSK3B P49841 1/20 0.39
STK10 O94804 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10714445 0.93 PTPN1 (0.50) PTPN1KDM4EALPLGAAPRKD3
SCHEMBL1050913 0.91 GSK3B (0.41) PTPN1KDM4EALPLGAAPRKD3
SCHEMBL929808 0.85 ALDH1A1 (0.41) PTPN1KDM4EALPLGAAPRKD3
SCHEMBL929420 0.83 ALDH1A1 (0.40) PTPN1KDM4EALPLGAAPRKD3
SCHEMBL8413957 0.83 MEN1 (0.44) PTPN1KDM4EPRKD3PRKCGPRKCB
SCHEMBL121405 0.82 GSK3B (0.50) PTPN1KDM4EPARP1POLBGSK3B
SCHEMBL27664385 0.82 GSK3B (0.50) PTPN1KDM4EPARP1POLBGSK3B
SCHEMBL28561353 0.82 PTPN1 (0.40) PTPN1KDM4EALPLGAAPRKD3
SCHEMBL28110313 0.82 GSK3B (0.40) PTPN1KDM4EALPLGAAPRKD3
SCHEMBL5405972 0.81 DNMT1 (0.45) KDM4EPRKD3PRKCGPRKCBPRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111978723-A Waterproof polyetherimide resin and preparation method thereof 南京康德祥医药科技有限公司 2020-11-24 CN claimed
CN-110724154-A Polysubstituted pyrrolo [3,4-d ] isoxazole derivative and synthetic method thereof 湖北科技学院 2020-01-24 CN claimed
CN-101503556-B Heat-resistant flame-retardant resin composition with improved glossiness and preparation method thereof PETROCHINA CO LTD 2012-03-07 CN claimed
CN-101503549-B Halogen substituent maleimide heat-resistant flame-retardant resin composition and preparation method thereof PETROCHINA CO LTD 2012-03-07 CN claimed
CN-101503545-B Halogen substituent maleimide heat-resistant flame-retardant resin composition with improved glossiness and preparation method thereof PETROCHINA CO LTD 2011-05-25 CN claimed
CN-101503547-B halogen substituent maleimide resin composition and preparation method thereof PETROCHINA CO LTD 2011-05-25 CN claimed
CN-101503542-B Heat-resistant flame-retardant resin composition and preparation method thereof PETROCHINA CO LTD 2011-05-25 CN claimed
CN-101503544-B Heat-resistant flame-retardant resin composition with improved glossiness and preparation method thereof PETROCHINA CO LTD 2011-01-12 CN claimed
CN-101503546-B Weather-resistant heat-resistant flame-retardant resin composition and preparation method thereof PETROCHINA CO LTD 2010-12-15 CN claimed
CN-101503554-B Weather-resistant halogen substituent maleimide heat-resistant flame-retardant resin composition and preparation method thereof PETROCHINA CO LTD 2010-12-15 CN claimed
CN-101503545-A Halogen substituent maleimide heat-resistant flame-retardant resin composition with improved glossiness and preparation method thereof PETROCHINA CO LTD (CN) 2009-08-12 CN claimed
CN-101503556-A Heat-resistant flame-retardant resin composition with improved glossiness and preparation method thereof PETROCHINA CO LTD (CN) 2009-08-12 CN claimed
CN-101503546-A Weather-resistant heat-resistant flame-retardant resin composition and preparation method thereof PETROCHINA CO LTD (CN) 2009-08-12 CN claimed
CN-101503550-A Halogen substituent maleimide heat-resistant flame-retardant resin composition and preparation method thereof PETROCHINA CO LTD (CN) 2009-08-12 CN claimed
CN-101503547-A Halogen substituent maleimide resin composition and preparation method thereof PETROCHINA CO LTD (CN) 2009-08-12 CN claimed
CN-101503549-A Halogen substituent maleimide heat-resistant flame-retardant resin composition and preparation method thereof PETROCHINA CO LTD (CN) 2009-08-12 CN claimed
CN-101503557-A Halogen substituent maleimide weather-proof heat-resistant flame-retardant resin composition and preparation method thereof PETROCHINA CO LTD (CN) 2009-08-12 CN claimed
CN-101503542-A Heat-resistant flame-retardant resin composition and preparation method thereof PETROCHINA CO LTD (CN) 2009-08-12 CN claimed
CN-101503554-A Weather-resistant halogen substituent maleimide heat-resistant flame-retardant resin composition and preparation method thereof PETROCHINA CO LTD (CN) 2009-08-12 CN claimed
WO-2008153243-A1 MALEIMIDE-ALPHA-ALKYLSTYRENE-BASED TERPOLYMER WITH LOW MOLTEN VISCOSITY AND CONTINUOUS BULK PROCESS FOR PRODUCING IT KOREA KUMHO PETROCHEMICAL CO., LTD (KR) 2008-12-18 WO claimed