Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 1/20 | 0.45 |
| ▸ | PRKCB | P05771 | 8/20 | 0.41 |
| ▸ | PRKCG | P05129 | 7/20 | 0.41 |
| ▸ | PRKCA | P17252 | 7/20 | 0.41 |
| ▸ | PRKCE | Q02156 | 7/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 6/20 | 0.41 |
| ▸ | PRKCH | P24723 | 6/20 | 0.41 |
| ▸ | PRKCI | P41743 | 6/20 | 0.41 |
| ▸ | PRKCQ | Q04759 | 6/20 | 0.41 |
| ▸ | PRKCZ | Q05513 | 6/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 6/20 | 0.41 |
| ▸ | PRKD1 | Q15139 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31669073 | 0.83 | CYP1A2 (0.42) | DNMT1PRKCBPRKCGPRKCAPRKCE | |
| SCHEMBL11882241 | 0.83 | PRKCB (0.40) | DNMT1PRKCBPRKCGPRKCAPRKCE | |
| SCHEMBL9228115 | 0.83 | CYP1A2 (0.42) | DNMT1PRKCBPRKCGPRKCAPRKCE | |
| SCHEMBL2544260 | 0.81 | PTPN1 (0.53) | DNMT1PRKCBPRKCGPRKCAPRKCE | |
| SCHEMBL9614313 | 0.79 | HPRT1 (0.44) | PRKCBPRKCGPRKCAPRKCEPRKD3 | |
| SCHEMBL1305138 | 0.79 | SIRT2 (0.40) | DNMT1PRKCBPRKCGPRKCAPRKCE | |
| SCHEMBL10714445 | 0.79 | PTPN1 (0.50) | DNMT1PRKCBPRKCGPRKCAPRKCE | |
| SCHEMBL8413954 | 0.77 | PARP1 (0.42) | DNMT1PRKCBPRKCGPRKCAPRKCE | |
| SCHEMBL3182292 | 0.77 | ALDH1A1 (0.44) | PRKCBPRKCGPRKCAPRKCEPRKD3 | |
| SCHEMBL27925210 | 0.77 | GSK3B (0.38) | DNMT1PRKCBPRKCGPRKCAPRKCE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7238489-B2 | Identification of sortase gene | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-07-03 | — | — | US | disclosed |
| EP-1646486-A2 | MEDICAL DEVICES AND PROCESSES FOR PREPARING SAME | Boston Scientific Limited (BB) | 2006-04-19 | — | — | EP | disclosed |
| WO-2005007375-A2 | MEDICAL DEVICES AND PROCESSES FOR PREPARING SAME | BOSTON SCIENTIFIC LIMITED (BB) | 2005-01-27 | — | — | WO | disclosed |
| EP-0422379-A2 | Thermosetting resin composition, resin sheet, prepreg and laminated sheet | NITTO DENKO CORPORATION (JP) | 1991-04-17 | — | — | EP | disclosed |