Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 16/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | GPR3 | P46089 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2960529 | 0.86 | PTPN1 (0.54) | PTPN1L3MBTL1LOXL2GPR3FABP4 | |
| SCHEMBL2542509 | 0.83 | PTPN1 (0.51) | PTPN1L3MBTL1LOXL2GPR3 | |
| SCHEMBL11900715 | 0.82 | LOXL2 (0.59) | PTPN1L3MBTL1LOXL2GPR3 | |
| SCHEMBL10758177 | 0.78 | PTPN1 (0.53) | PTPN1L3MBTL1LOXL2 | |
| SCHEMBL10755869 | 0.76 | PTPN1 (0.56) | PTPN1 | |
| SCHEMBL10756975 | 0.75 | PTPN1 (0.51) | PTPN1L3MBTL1LOXL2FABP4FABP5 | |
| Oxalic Acid SCHEMBL10753837 | 0.75 | PTPN1 (0.54) | PTPN1 | |
| Hydrochloric Acid SCHEMBL7980948 | 0.75 | PTPN1 (0.51) | PTPN1 | |
| SCHEMBL17921221 | 0.75 | LOXL2 (0.65) | PTPN1L3MBTL1LOXL2GPR3 | |
| SCHEMBL4851404 | 0.75 | PTGS2 (0.42) | PTPN1LOXL2GPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2673269-A1 | HETEROCYCLIC COMPOUNDS AS PI3 KINASE INHIBITORS | F.HOFFMANN-LA ROCHE AG (CH) | 2013-12-18 | — | — | EP | disclosed |
| EP-2552908-A2 | HETEROCYCLIC COMPOUNDS AND THEIR USES | Amgen Inc. (US) | 2013-02-06 | — | — | EP | disclosed |
| WO-2012107465-A1 | HETEROCYCLIC COMPOUNDS AS PI3 KINASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2012-08-16 | — | — | WO | disclosed |
| WO-2011123751-A2 | HETEROCYCLIC COMPOUNDS AND THEIR USES | AMGEN INC. (US) | 2011-10-06 | — | — | WO | disclosed |