Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | DPP4 | P27487 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25443710 | 0.86 | ALDH1A1 (0.48) | POLBKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL25443709 | 0.84 | MAPT (0.52) | POLBRAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL25443733 | 0.84 | CYP2C9 (0.53) | POLBKDM4ECYP2C9CYP2C19RAB9A | |
| SCHEMBL2767991 | 0.84 | ME2 (0.58) | POLBKDM4ECYP2C9CYP2C19RAB9A | |
| SCHEMBL25443708 | 0.83 | MAPT (0.55) | POLBRAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL23544870 | 0.82 | KDM4E (0.56) | POLBKDM4ECYP2C9CYP2C19RAB9A | |
| SCHEMBL14444869 | 0.82 | KDM4E (0.75) | KDM4ECYP2C9CYP2C19RAB9AKMT2A | |
| SCHEMBL25443707 | 0.82 | MAPT (0.53) | POLBRAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL25443706 | 0.82 | MAPT (0.53) | POLBRAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL21955417 | 0.82 | KMT2A (0.54) | POLBKDM4ECYP2C9CYP2C19RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230146870-A1 | METHOD TO QUANTIFY AFFINITY AND SELECTIVITY OF SMALL MOLECULES FOR PROTEINS IN LIVING CELLS | OHIO STATE INNOVATION FOUNDATION | 2023-05-11 | — | — | US | disclosed |
| US-20230146870-A1 | METHOD TO QUANTIFY AFFINITY AND SELECTIVITY OF SMALL MOLECULES FOR PROTEINS IN LIVING CELLS | OHIO STATE INNOVATION FOUNDATION | 2023-05-11 | — | — | US | disclosed |