Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 5/20 | 0.48 |
| ▸ | HTR7 | P34969 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25443731 | 0.93 | MAPT (0.51) | MEN1KMT2AALDH1A1SMN1; SMN2HTR1A | |
| SCHEMBL25443730 | 0.92 | MAPT (0.53) | MEN1KMT2AALDH1A1SMN1; SMN2HTR1A | |
| SCHEMBL25443727 | 0.91 | MAPT (0.52) | MEN1KMT2AALDH1A1SMN1; SMN2HTR1A | |
| SCHEMBL25443729 | 0.91 | MAPT (0.52) | MEN1KMT2AALDH1A1SMN1; SMN2HTR1A | |
| SCHEMBL25443733 | 0.88 | CYP2C9 (0.53) | MEN1KMT2AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL25444164 | 0.86 | MAPT (0.54) | MEN1KMT2AALDH1A1SMN1; SMN2HTR1A | |
| SCHEMBL25443710 | 0.85 | ALDH1A1 (0.48) | MEN1KMT2AALDH1A1HTR1AHTR7 | |
| SCHEMBL25443746 | 0.83 | P2RX7 (0.40) | MEN1KMT2AALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL15840436 | 0.82 | MAPT (0.69) | MEN1KMT2AALDH1A1SMN1; SMN2HTR1A | |
| SCHEMBL22209344 | 0.79 | HTR2C (0.62) | MEN1KMT2AALDH1A1HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230146870-A1 | METHOD TO QUANTIFY AFFINITY AND SELECTIVITY OF SMALL MOLECULES FOR PROTEINS IN LIVING CELLS | OHIO STATE INNOVATION FOUNDATION | 2023-05-11 | — | — | US | disclosed |
| US-20230146870-A1 | METHOD TO QUANTIFY AFFINITY AND SELECTIVITY OF SMALL MOLECULES FOR PROTEINS IN LIVING CELLS | OHIO STATE INNOVATION FOUNDATION | 2023-05-11 | — | — | US | disclosed |