Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25443740 | 1.00 | MEN1 (0.39) | MEN1KMT2AP2RX7ALDH1A1HPGD | |
| SCHEMBL25443744 | 0.99 | MEN1 (0.39) | MEN1KMT2AP2RX7ALDH1A1HPGD | |
| SCHEMBL25443745 | 0.96 | MEN1 (0.40) | MEN1KMT2AP2RX7ALDH1A1HPGD | |
| SCHEMBL25443746 | 0.92 | P2RX7 (0.40) | MEN1KMT2AP2RX7ALDH1A1HPGD | |
| SCHEMBL25444274 | 0.91 | PLA2G2A (0.40) | MEN1KMT2AP2RX7ALDH1A1HPGD | |
| SCHEMBL25443748 | 0.85 | P2RX7 (0.42) | MEN1KMT2AP2RX7ALDH1A1HPGD | |
| SCHEMBL25443729 | 0.84 | MAPT (0.52) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL25443727 | 0.84 | MAPT (0.52) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL25443730 | 0.83 | MAPT (0.53) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL25444273 | 0.81 | P2RX7 (0.40) | MEN1KMT2AP2RX7ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230146870-A1 | METHOD TO QUANTIFY AFFINITY AND SELECTIVITY OF SMALL MOLECULES FOR PROTEINS IN LIVING CELLS | OHIO STATE INNOVATION FOUNDATION | 2023-05-11 | — | — | US | disclosed |