Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19116542 | 0.86 | SMN1; SMN2 (0.55) | PTPN1SMN1; SMN2HPGDRAB9ANPC1 | |
| SCHEMBL19116525 | 0.84 | RAB9A (0.62) | SMN1; SMN2HPGDRAB9ANPC1L3MBTL1 | |
| SCHEMBL19116519 | 0.84 | DEGS1 (0.66) | PTPN1SMN1; SMN2HPGDRAB9ANPC1 | |
| SCHEMBL19116341 | 0.84 | PTPN1 (0.67) | PTPN1SMN1; SMN2HPGDLMNARAB9A | |
| SCHEMBL31052440 | 0.83 | PTPN1 (0.65) | PTPN1SMN1; SMN2HPGDLMNARAB9A | |
| SCHEMBL20964577 | 0.83 | RAB9A (0.75) | SMN1; SMN2HPGDLMNARAB9ANPC1 | |
| SCHEMBL19116851 | 0.83 | PTPN1 (0.65) | PTPN1SMN1; SMN2HPGDLMNARAB9A | |
| SCHEMBL8792557 | 0.81 | HSD17B10 (0.76) | SMN1; SMN2HSD17B10LMNARAB9ANPC1 | |
| SCHEMBL19116804 | 0.81 | KMT2A (0.71) | PTPN1SMN1; SMN2LMNARAB9ANPC1 | |
| SCHEMBL21765873 | 0.80 | PTPN1 (0.88) | PTPN1SMN1; SMN2HPGDLMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230146870-A1 | METHOD TO QUANTIFY AFFINITY AND SELECTIVITY OF SMALL MOLECULES FOR PROTEINS IN LIVING CELLS | OHIO STATE INNOVATION FOUNDATION | 2023-05-11 | — | — | US | disclosed |