Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.75 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.75 |
| ▸ | NPC1 | O15118 | 4/20 | 0.75 |
| ▸ | THRB | P10828 | 1/20 | 0.75 |
| ▸ | HPGD | P15428 | 1/20 | 0.75 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19116519 | 0.83 | DEGS1 (0.66) | RAB9AL3MBTL1NPC1THRBHPGD | |
| SCHEMBL19116525 | 0.83 | RAB9A (0.62) | RAB9AL3MBTL1NPC1THRBHPGD | |
| SCHEMBL25443769 | 0.83 | PTPN1 (0.67) | RAB9AL3MBTL1NPC1THRBHPGD | |
| SCHEMBL19090370 | 0.82 | TDP1 (0.73) | RAB9AL3MBTL1NPC1HPGDTDP1 | |
| SCHEMBL19116542 | 0.81 | SMN1; SMN2 (0.55) | RAB9AL3MBTL1NPC1THRBHPGD | |
| SCHEMBL23933096 | 0.81 | TDP1 (1.00) | RAB9AL3MBTL1NPC1HPGDTDP1 | |
| SCHEMBL29883158 | 0.80 | TDP1 (0.71) | RAB9AL3MBTL1NPC1HPGDTDP1 | |
| SCHEMBL2188598 | 0.80 | TDP1 (0.71) | RAB9AL3MBTL1NPC1HPGDTDP1 | |
| SCHEMBL2944497 | 0.80 | TDP1 (0.71) | RAB9AL3MBTL1NPC1HPGDTDP1 | |
| SCHEMBL19099330 | 0.79 | SMN1; SMN2 (0.53) | RAB9AL3MBTL1NPC1THRBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10851096-B2 | Aryl and heteroaryl amides for use as anti-proliferative, anti-thrombotic, and anti-viral agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2020-12-01 | — | — | US | disclosed |
| US-20190127361-A1 | Therapeutic Compounds | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2019-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190127361-A1 | Therapeutic Compounds | SDHA, SLC10A1, SERPINC1 | RAB9A 426/4885L3MBTL1 4755/4885NPC1 11/4885 |
| US-10851096-B2 | Aryl and heteroaryl amides for use as anti-proliferative, anti-thrombotic, and anti-viral agents | SERPINC1, F12, RPL35 | RAB9A 2041/4885L3MBTL1 4517/4885NPC1 2196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.