Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25444068 | 1.00 | MAPT (0.52) | MAPTLMNANPSR1HDAC1GAA | |
| SCHEMBL25444056 | 0.88 | MAPT (0.55) | MAPTLMNANPSR1HDAC1ALDH1A1 | |
| SCHEMBL25443707 | 0.87 | MAPT (0.53) | MAPTLMNANPSR1HDAC1GAA | |
| SCHEMBL25443706 | 0.87 | MAPT (0.53) | MAPTLMNANPSR1HDAC1GAA | |
| SCHEMBL25443708 | 0.85 | MAPT (0.55) | MAPTLMNANPSR1HDAC1GAA | |
| SCHEMBL25443709 | 0.81 | MAPT (0.52) | MAPTLMNANPSR1HDAC1GAA | |
| SCHEMBL8972662 | 0.77 | GNAI3 (0.51) | MAPTLMNANPSR1ALDH1A1MEN1 | |
| SCHEMBL25443710 | 0.76 | ALDH1A1 (0.48) | MAPTLMNANPSR1GAAPOLB | |
| SCHEMBL25443727 | 0.76 | MAPT (0.52) | MAPTLMNANPSR1ALDH1A1HTR1A | |
| SCHEMBL25443729 | 0.76 | MAPT (0.52) | MAPTLMNANPSR1ALDH1A1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230146870-A1 | METHOD TO QUANTIFY AFFINITY AND SELECTIVITY OF SMALL MOLECULES FOR PROTEINS IN LIVING CELLS | OHIO STATE INNOVATION FOUNDATION | 2023-05-11 | — | — | US | disclosed |