Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 4/20 | 0.52 |
| ▸ | CRBN | Q96SW2 | 11/20 | 0.52 |
| ▸ | DDB1 | Q16531 | 9/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL30440705 | 0.97 | STAT3 (0.49) | STAT3CRBNDDB1MAPTIRAK4 | |
| Hydrochloric Acid SCHEMBL30441024 | 0.94 | CRBN (0.54) | STAT3CRBNDDB1 | |
| Formic Acid SCHEMBL30440658 | 0.91 | CRBN (0.52) | STAT3CRBNDDB1 | |
| SCHEMBL25446362 | 0.90 | STAT3 (0.49) | STAT3CRBNDDB1MAPTIRAK4 | |
| SCHEMBL22276609 | 0.84 | CRBN (0.70) | STAT3CRBNDDB1MAPT | |
| SCHEMBL27208479 | 0.84 | CRBN (0.53) | STAT3CRBNDDB1MAPT | |
| SCHEMBL21459015 | 0.84 | CRBN (0.52) | CRBNDDB1MAPTIRAK4 | |
| SCHEMBL21458818 | 0.84 | CRBN (0.52) | CRBNDDB1MAPTIRAK4 | |
| SCHEMBL21771120 | 0.84 | MAPT (0.55) | CRBNDDB1MAPT | |
| SCHEMBL21472007 | 0.84 | MAPT (0.55) | CRBNDDB1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081476-A1 | METHODS AND COMPOSITIONS FOR TARGETED PROTEIN DEGRADATION | RANOK THERAPEUTICS (HANGZHOU) CO. LTD. (CN) | 2023-05-11 | — | — | WO | disclosed |