Formic Acid

Formic Acid

SCHEMBL30440658

O=C1CCC(N2C(=O)c3ccc(OCCNC(=O)C4CCNCC4)cc3C2=O)C(=O)N1.O=CO

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 18/20 0.52
DDB1 Q16531 15/20 0.52
ALDH1A1 P00352 1/20 0.45
CHRM2 P08172 1/20 0.45
OPRM1 P35372 1/20 0.45
IKZF3 Q9UKT9 1/20 0.45
CYP1A2 P05177 1/20 0.45
TSHR P16473 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
STAT3 P40763 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL30441024 0.96 CRBN (0.54) CRBNDDB1ALDH1A1CHRM2OPRM1
Formic Acid SCHEMBL30440705 0.95 STAT3 (0.49) CRBNDDB1STAT3
SCHEMBL25446263 0.91 STAT3 (0.52) CRBNDDB1STAT3
SCHEMBL23705709 0.84 CRBN (0.59) CRBNDDB1ALDH1A1CHRM2OPRM1
Formic Acid SCHEMBL29617066 0.83 CRBN (0.53) CRBNDDB1ALDH1A1CHRM2OPRM1
Formic Acid SCHEMBL23705607 0.83 CRBN (0.53) CRBNDDB1ALDH1A1CHRM2OPRM1
SCHEMBL29646009 0.82 CRBN (0.59) CRBNDDB1ALDH1A1CHRM2OPRM1
SCHEMBL25446362 0.82 STAT3 (0.49) CRBNDDB1STAT3
Formic Acid SCHEMBL23705587 0.81 CRBN (0.52) CRBNDDB1ALDH1A1CHRM2OPRM1
Formic Acid SCHEMBL30058723 0.81 CRBN (0.52) CRBNDDB1ALDH1A1CHRM2OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023077441-A1 METHODS AND COMPOSITIONS FOR TARGETED PROTEIN DEGRADATION RANOK THERAPEUTICS (HANGZHOU) CO. LTD. (CN) 2023-05-11 WO disclosed