Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.35 |
| ▸ | USP2 | O75604 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16877522 | 0.97 | ALDH1A1 (0.44) | ALDH1A1CXCR4SMN1; SMN2CYP2D6USP2 | |
| SCHEMBL16877454 | 0.97 | ALDH1A1 (0.44) | ALDH1A1CXCR4SMN1; SMN2CYP2D6USP2 | |
| SCHEMBL17797618 | 0.94 | ALDH1A1 (0.50) | ALDH1A1CXCR4SMN1; SMN2CYP2D6USP2 | |
| SCHEMBL16878003 | 0.94 | ALDH1A1 (0.39) | ALDH1A1CXCR4SMN1; SMN2CYP2D6USP2 | |
| SCHEMBL28081 | 0.94 | CYP2D6 (0.38) | ALDH1A1CXCR4SMN1; SMN2CYP2D6USP2 | |
| SCHEMBL18389567 | 0.91 | ALDH1A1 (0.44) | ALDH1A1CXCR4SMN1; SMN2CYP2D6USP2 | |
| SCHEMBL13459460 | 0.91 | ALDH1A1 (0.44) | ALDH1A1CXCR4SMN1; SMN2CYP2D6USP2 | |
| SCHEMBL10051063 | 0.91 | ALDH1A1 (0.44) | ALDH1A1CXCR4SMN1; SMN2CYP2D6USP2 | |
| SCHEMBL503331 | 0.90 | ALDH1A1 (0.41) | ALDH1A1CYP2D6USP2CYP3A4TSHR | |
| SCHEMBL503822 | 0.90 | ALDH1A1 (0.41) | ALDH1A1CXCR4SMN1; SMN2CYP2D6USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230147833-A1 | OPTICALLY PURE OXASPIRO-SUBSTITUTED PYRROLOPYRAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | YANGTZE RIVER PHARMACEUTICAL GROUP CO., LTD. (CN) | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230147833-A1 | OPTICALLY PURE OXASPIRO-SUBSTITUTED PYRROLOPYRAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | WEE1, CYP51A1, CYP4F11 | ALDH1A1 333/4885CXCR4 1035/4885SMN1; SMN2 4162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.