SCHEMBL28081

SCHEMBL28081

C1CCC2(C1)CCNCC2

nearest known ligand 0.93

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 5/20 0.38
USP2 O75604 2/20 0.38
ALDH1A1 P00352 4/20 0.38
TSHR P16473 4/20 0.38
CYP3A4 P08684 3/20 0.38
CYP1A2 P05177 2/20 0.38
CYP2C19 P33261 2/20 0.38
HSD17B10 Q99714 1/20 0.36
CXCR4 P61073 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CYP2C9 P11712 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL503331 0.97 ALDH1A1 (0.41) CYP2D6USP2ALDH1A1TSHRCYP3A4
Hydrochloric Acid SCHEMBL1456309 0.97 CYP2D6 (0.37) CYP2D6USP2ALDH1A1TSHRCYP3A4
SCHEMBL20416526 0.97 ALDH1A1 (0.41) CYP2D6USP2ALDH1A1TSHRCYP3A4
SCHEMBL26952 0.97 ALDH1A1 (0.41) CYP2D6USP2ALDH1A1TSHRCYP3A4
SCHEMBL25447178 0.94 ALDH1A1 (0.47) CYP2D6USP2ALDH1A1TSHRCYP3A4
SCHEMBL16878003 0.94 ALDH1A1 (0.39) CYP2D6USP2ALDH1A1TSHRCYP3A4
Hydrochloric Acid SCHEMBL3377703 0.94 ALDH1A1 (0.39) CYP2D6USP2ALDH1A1TSHRCYP3A4
SCHEMBL20160562 0.94 ALDH1A1 (0.39) CYP2D6USP2ALDH1A1TSHRCYP3A4
SCHEMBL1797025 0.93
SCHEMBL10051063 0.91 ALDH1A1 (0.44) CYP2D6USP2ALDH1A1TSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1387 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122070278-A Bifunctional protein degradation agent containing aryl substituted heteroaryl and application thereof 标新生物医药科技(上海)有限公司 2026-05-19 CN claimed
CN-120202200-A Oxo-isoindolinyl substituted tetrahydropyrimidinedione-based compounds and applications thereof 标新生物医药科技(上海)有限公司 2025-06-24 CN claimed
WO-2025108157-A1 PHARMACEUTICAL USE OF GUAIANE SESQUITERPENE DERIVATIVE 南京中医药大学 2025-05-30 WO claimed
CN-119654316-A Thioglutarimide isoindolinone skeleton-based compound and application thereof 标新生物医药科技(上海)有限公司 2025-03-18 CN claimed
CN-119451952-A Oxo-isoindolinyl substituted tetrahydropyrimidinedione derivative and application thereof 标新生物医药科技(上海)有限公司 2025-02-14 CN claimed
EP-4446324-A1 LIGAND COMPOUNDS FOR E3 UBIQUITIN LIGASE, PROTEIN DEGRADERS DEVELOPED ON BASIS OF LIGAND COMPOUNDS, AND USES THEREOF Gluetacs Therapeutics (Shanghai) Co., Ltd. (CN) 2024-10-16 EP claimed
CN-118384154-A Application of guaiane sesquiterpene derivative in preparation of medicines for treating inflammatory diseases 南京中医药大学 2024-07-26 CN claimed
CN-118319903-A Application of guaiane sesquiterpene derivative in preparation of medicines for treating inflammatory diseases 南京中医药大学 2024-07-12 CN claimed
WO-2024044486-A1 JAK2 INHIBITOR COMPOUNDS AJAX THERAPEUTICS, INC. (US) 2024-02-29 WO claimed
EP-4298095-A1 HETEROCYCLIC COMPOUNDS AS KINASE INHIBITOR AND USES THEREOF Sperogenix Therapeutics Limited (HK) 2024-01-03 EP claimed
WO-2002048109-A2 N-ALKOXY-4,4-DIOXY-POLYALKYL-PIPERIDINES AS RADICAL POLYMERIZATION INITIATORS CIBA SPECIALTY CHEMICLAS HOLDING INC. (CH) 2002-06-20 WO claimed
EP-0765312-A1 4-CARBAMOYLOXY-PIPERIDINE-1-CARBOXYLIC ACID ESTERS: INHIBITORS OF CHOLESTEROL ABSORPTION AMERICAN HOME PRODUCTS CORPORATION (US) 1997-04-02 EP claimed
US-5527804-A 4-carbamoyloxy-piperidine-1-carboxylic acid esters: inhibitors or cholesterol absorption AMERICAN HOME PRODUCTS CORPORATION (US) 1996-06-18 US claimed
WO-1995034539-A1 4-CARBAMOYLOXY-PIPERIDINE-1-CARBOXYLIC ACID ESTERS: INHIBITORS OF CHOLESTEROL ABSORPTION AMERICAN HOME PRODUCTS CORPORATION (US) 1995-12-21 WO claimed
US-4855302-A 8-((4-(INDOL-3-YL)PIPERIDINO)ALKYL)-8-AZASPIRO(4.5)DECANE-7,9 -DIONES ROUSSEL UCLAF (FR) 1989-08-08 US claimed
EP-0095076-B1 POLYALKYLDIAZASPIRODECANYL-ACETIC-ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS LIGHT PROTECTING AGENTS FOR ORGANIC POLYMERS HOECHST AKTIENGESELLSCHAFT (DE) 1987-04-01 EP claimed
US-4562220-A LOW VOLATILITY AND HIGH COMPATIBILITY HOECHST AKTIENGESELLSCHAFT (DE) 1985-12-31 US claimed
EP-0008102-B1 PROCESS FOR THE PREPARATION OF AZASPIRODECANES HOECHST AKTIENGESELLSCHAFT (DE) 1981-09-30 EP claimed
US-4220773-A Process for the manufacture of aza-spirodecanes HOECHST AKTIENGESELLSCHAFT (DE) 1980-09-02 US claimed
US-4104380-A Dibenzyl glycolic acid derivatives WARNER-LAMBERT COMPANY (US) 1978-08-01 US claimed