Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.41 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.41 |
| ▸ | TNK1 | Q13470 | 2/20 | 0.41 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25173240 | 0.89 | ALDH1A1 (0.53) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL21245661 | 0.87 | ALDH1A1 (0.61) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL1640562 | 0.85 | ALDH1A1 (0.60) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL25447375 | 0.84 | ALDH1A1 (0.55) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL30306129 | 0.81 | ALDH1A1 (0.57) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL22471238 | 0.81 | ALDH1A1 (0.57) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL24267643 | 0.81 | ALDH1A1 (0.57) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL26655535 | 0.81 | ALDH1A1 (0.57) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL25169824 | 0.81 | ALDH1A1 (0.47) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL31334229 | 0.80 | MAPT (0.46) | ALDH1A1KMT2ALMNAMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230145336-A1 | BRAF DEGRADERS | C4 THERAPEUTICS, INC. (US) | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230145336-A1 | BRAF DEGRADERS | BRAF, NRAS, RAF1 | ALDH1A1 1704/4885KMT2A 738/4885LMNA 3688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.