Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.33 |
| ▸ | ACP1 | P24666 | 3/20 | 0.33 |
| ▸ | CDC25B | P30305 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | FASN | P49327 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19432225 | 0.61 | HSD17B10 (0.35) | — | |
| SCHEMBL11484364 | 0.60 | MMP2 (0.46) | MEN1KMT2AGAAALOX12ALDH1A1 | |
| SCHEMBL11146108 | 0.60 | MMP2 (0.46) | MEN1KMT2AGAAALOX12ALDH1A1 | |
| SCHEMBL8893756 | 0.60 | MMP2 (0.46) | MEN1KMT2AGAAALOX12ALDH1A1 | |
| SCHEMBL1404434 | 0.60 | MMP2 (0.46) | MEN1KMT2AGAAALOX12ALDH1A1 | |
| SCHEMBL25205553 | 0.58 | SIRT2 (0.38) | PTPN1ACP1CDC25B | |
| SCHEMBL27990757 | 0.58 | PTPN1 (0.34) | PTPN1ACP1CDC25BMEN1KMT2A | |
| SCHEMBL8920856 | 0.58 | SIRT2 (0.38) | PTPN1ACP1CDC25B | |
| SCHEMBL28067498 | 0.57 | SIRT2 (0.39) | PTPN1ACP1CDC25BMEN1KMT2A | |
| SCHEMBL7553174 | 0.57 | SMN1; SMN2 (0.45) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2370113-A1 | PACKAGING SOLUTIONS | Bausch & Lomb Incorporated (US) | 2011-10-05 | — | — | EP | disclosed |
| WO-2010078150-A1 | PACKAGING SOLUTIONS | BAUSCH & LOMB INCORPORATED (US) | 2010-07-08 | — | — | WO | disclosed |