SCHEMBL7553174

SCHEMBL7553174

CCCCCC1(C)NC(=O)NC1=O

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
ALDH1A1 P00352 1/20 0.44
MMP2 P08253 6/20 0.44
MMP9 P14780 6/20 0.44
MMP3 P08254 1/20 0.44
AKR1B1 P15121 1/20 0.43
MMP8 P22894 4/20 0.42
MMP13 P45452 4/20 0.42
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8893756 0.98 MMP2 (0.46) SMN1; SMN2NPSR1ALDH1A1MMP2MMP9
SCHEMBL11484364 0.98 MMP2 (0.46) SMN1; SMN2NPSR1ALDH1A1MMP2MMP9
SCHEMBL5611492 0.98 MMP2 (0.46) SMN1; SMN2NPSR1ALDH1A1MMP2MMP9
SCHEMBL11146108 0.98 MMP2 (0.46) SMN1; SMN2NPSR1ALDH1A1MMP2MMP9
SCHEMBL1404434 0.98 MMP2 (0.46) SMN1; SMN2NPSR1ALDH1A1MMP2MMP9
SCHEMBL6691265 0.94 SMN1; SMN2 (0.46) SMN1; SMN2NPSR1ALDH1A1MMP2MMP9
SCHEMBL1404438 0.85 SMN1; SMN2 (0.49) SMN1; SMN2NPSR1ALDH1A1MMP2AKR1B1
SCHEMBL11571309 0.83 SMN1; SMN2 (0.39) SMN1; SMN2NPSR1ALDH1A1MMP2MMP9
SCHEMBL901435 0.81
SCHEMBL9190800 0.80 SMN1; SMN2 (0.45) SMN1; SMN2NPSR1ALDH1A1MMP2AKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0156582-B1 PROCESS FOR THE PREPARATION OF DL-BETA-ARYL AMINO ACIDS ALKALOIDA VEGYESZETI GYAR (HU) 1988-09-14 EP claimed
US-4745189-A Method of preparing N-halogenated organic heterocyclic compounds ETHYL CORPORATION (US) 1988-05-17 US claimed
US-4647694-A Process for the preparation of D1-β-aryl amino acids ALKALOIDA VEGYESZETI GYAR (HU) 1987-03-03 US claimed
EP-0156582-A1 Process for the preparation of dl-beta-aryl amino acids ALKALOIDA VEGYESZETI GYAR (HU) 1985-10-02 EP claimed
US-4308341-A PROVIDING ISOINDOZE DYES BY REACTION OF COBALT AMINE LIGANDS AND AROMATIC DIALDEHYDES EASTMAN KODAK COMPANY (US) 1981-12-29 US claimed
US-20020079457-A1 X-RAY IMAGE RECORDING SYSTEM AND X-RAY IMAGE RECORDING METHOD KONICA CORPORATION (JP) 2002-06-27 US disclosed
US-6410921-B1 X-ray image recording system and x-ray image recording method KONICA CORPORATION (JP) 2002-06-25 US disclosed
US-5698363-A IMAGEWISE PROVIDING IN SECOND LAYER COMPONENT NOT IN FIRST LAYER, SELECTED FROM COBALT COMPLEX HAVING AMMONIA OR PRIMARY AMINE LIGAND, COMPOUND HAVING ABSORPTION WAVELENGTH CHANGED BY LIGAND, COMPOUND CAUSING LIGAND TO BE RELEASED KONICA CORPORATION (JP) 1997-12-16 US disclosed
WO-1997043264-A1 COMPOSITIONS AND METHODS UTILIZING 1,3-BROMOCHLORO-5-METHYL-5-PROPYLHYDANTOIN GREAT LAKES CHEMICAL CORPORATION (US) 1997-11-20 WO disclosed
EP-0753415-A2 Image forming method KONICA CORPORATION (JP) 1997-01-15 EP disclosed
US-5476755-A Exposing to light for development, heating for fixing and acid treatment; photoreduction of cobalt complex KONICA CORPORATION (JP) 1995-12-19 US disclosed
EP-0156582-B1 PROCESS FOR THE PREPARATION OF DL-BETA-ARYL AMINO ACIDS ALKALOIDA VEGYESZETI GYAR (HU) 1988-09-14 EP disclosed
US-4647694-A Process for the preparation of D1-β-aryl amino acids ALKALOIDA VEGYESZETI GYAR (HU) 1987-03-03 US disclosed
EP-0156582-A1 Process for the preparation of dl-beta-aryl amino acids ALKALOIDA VEGYESZETI GYAR (HU) 1985-10-02 EP disclosed
EP-0156582-A1 Process for the preparation of dl-beta-aryl amino acids ALKALOIDA VEGYESZETI GYAR (HU) 1985-10-02 EP disclosed
US-4308341-A PROVIDING ISOINDOZE DYES BY REACTION OF COBALT AMINE LIGANDS AND AROMATIC DIALDEHYDES EASTMAN KODAK COMPANY (US) 1981-12-29 US disclosed
US-4150234-A WATER RESISTANT CIBA-GEIGY CORPORATION (US) 1979-04-17 US disclosed
US-4137139-A WATER RESISTANT LAMINATES, ADHESIVES, COATINGS CIBA-GEIGY CORPORATION (US) 1979-01-30 US disclosed
US-4071477-A CASTING AND LAMINATING RESINS CIBA-GEIGY CORPORATION (US) 1978-01-31 US disclosed
US-3966627-A ALUMINUM SILICATE, BUILDER SALT COLGATE-PALMOLIVE COMPANY (US) 1976-06-29 US disclosed