Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.57 |
| ▸ | APP | P05067 | 1/20 | 0.56 |
| ▸ | FBP1 | P09467 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.46 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2544845 | 1.00 | PTGS2 (0.57) | PTGS2APPFBP1NPC1MAPT | |
| SCHEMBL15689017 | 0.90 | PTGS2 (0.54) | PTGS2APPFBP1NPC1MAPT | |
| SCHEMBL15689016 | 0.90 | PTGS2 (0.54) | PTGS2APPFBP1NPC1MAPT | |
| SCHEMBL10557392 | 0.89 | APP (0.64) | PTGS2APPFBP1NPC1MAPT | |
| SCHEMBL10557386 | 0.89 | APP (0.64) | PTGS2APPFBP1NPC1MAPT | |
| SCHEMBL6437741 | 0.88 | PTGS2 (0.53) | PTGS2APPFBP1NPC1MAPT | |
| SCHEMBL6437682 | 0.88 | PTGS2 (0.53) | PTGS2APPFBP1NPC1MAPT | |
| SCHEMBL6437684 | 0.88 | PTGS2 (0.53) | PTGS2APPFBP1NPC1MAPT | |
| SCHEMBL8670886 | 0.87 | PTGS2 (0.51) | PTGS2APPFBP1NPC1MAPT | |
| SCHEMBL15688633 | 0.87 | PTGS2 (0.51) | PTGS2APPFBP1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110263879-A1 | ZWITTERIONIC PHOSPHONIUM SALTS | THE HONG KONG POLYTECHNIC UNIVERSITY (HK) | 2011-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263879-A1 | ZWITTERIONIC PHOSPHONIUM SALTS | CX3CR1, PHOSPHO1, CBR3 | PTGS2 4164/4885APP 699/4885FBP1 373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.