Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 2/20 | 0.43 |
| ▸ | JAK1 | P23458 | 2/20 | 0.43 |
| ▸ | TYK2 | P29597 | 2/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | POLA1 | P09884 | 1/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.41 |
| ▸ | TLR4 | O00206 | 1/20 | 0.41 |
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
| ▸ | CTSC | P53634 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30502751 | 1.00 | MEN1 (0.48) | MEN1KMT2ANPC1RAB9AMAPK10 | |
| SCHEMBL31220846 | 0.85 | KMT2A (0.63) | MEN1KMT2ANPC1RAB9AMAPK10 | |
| SCHEMBL7981759 | 0.85 | KMT2A (0.63) | MEN1KMT2ANPC1RAB9AMAPK10 | |
| SCHEMBL29408384 | 0.81 | EGFR (0.52) | MEN1KMT2ANPC1RAB9AMAPK10 | |
| SCHEMBL30502777 | 0.81 | CYP3A4 (0.50) | MEN1KMT2ANPC1RAB9AMAPK10 | |
| SCHEMBL25453078 | 0.81 | CYP3A4 (0.50) | MEN1KMT2ANPC1RAB9AMAPK10 | |
| SCHEMBL28415105 | 0.81 | EGFR (0.52) | MEN1KMT2ANPC1RAB9AMAPK10 | |
| SCHEMBL3038970 | 0.77 | PIM1 (0.52) | MEN1KMT2ANPC1RAB9AMAPK10 | |
| SCHEMBL11593134 | 0.76 | CYP3A4 (0.54) | POLA1 | |
| SCHEMBL3888498 | 0.75 | MEN1 (0.55) | MEN1KMT2AMAPK10GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081800-A1 | ALPHA-2A ADRENERGIC RECEPTOR MODULATORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-05-11 | — | — | WO | disclosed |