Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.63 |
| ▸ | MEN1 | O00255 | 5/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.55 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | POLA1 | P09884 | 1/20 | 0.49 |
| ▸ | KMO | O15229 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | JAK1 | P23458 | 1/20 | 0.46 |
| ▸ | TYK2 | P29597 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31220846 | 1.00 | KMT2A (0.63) | KMT2AMEN1RAB9ANPC1GRM4 | |
| Acetic Acid SCHEMBL9839206 | 0.87 | KMT2A (0.61) | KMT2AMEN1RAB9ANPC1GRM4 | |
| SCHEMBL28415105 | 0.85 | EGFR (0.52) | KMT2AMEN1RAB9ANPC1GRM4 | |
| SCHEMBL3038970 | 0.85 | PIM1 (0.52) | KMT2AMEN1RAB9ANPC1GRM4 | |
| SCHEMBL29408384 | 0.85 | EGFR (0.52) | KMT2AMEN1RAB9ANPC1GRM4 | |
| SCHEMBL25453077 | 0.85 | MEN1 (0.48) | KMT2AMEN1RAB9ANPC1GRM4 | |
| SCHEMBL30502751 | 0.85 | MEN1 (0.48) | KMT2AMEN1RAB9ANPC1GRM4 | |
| SCHEMBL7765065 | 0.79 | HDAC3 (0.55) | KMT2AMEN1RAB9ANPC1GRM4 | |
| SCHEMBL21258999 | 0.79 | NPC1 (0.60) | KMT2AMEN1RAB9ANPC1MAPK10 | |
| SCHEMBL29850051 | 0.79 | NPC1 (0.60) | KMT2AMEN1RAB9ANPC1MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235730-B1 | ANTICHOLESTEROL AGENT, ANTILIPEMIC AGENT | JAPAN TOBACCO, INC. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0970954-A1 | 3-PIPERIDYL-4-OXOQUINAZOLINE DERIVATIVES AND MEDICINCAL COMPOSITIONS CONTAINING THE SAME | JAPAN TOBACCO INC. (JP) | 2000-01-12 | — | — | EP | disclosed |