Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30502777 | 1.00 | CYP3A4 (0.50) | CYP3A4ALDH1A1THRBALOX15RECQL | |
| SCHEMBL25175479 | 0.85 | RAB9A (0.63) | CYP3A4ALDH1A1RAB9ANPSR1MEN1 | |
| SCHEMBL25453077 | 0.81 | MEN1 (0.48) | RAB9AMEN1MAPK10GFERKMT2A | |
| SCHEMBL30502751 | 0.81 | MEN1 (0.48) | RAB9AMEN1MAPK10GFERKMT2A | |
| SCHEMBL2309841 | 0.81 | RAB9A (0.48) | CYP3A4ALDH1A1RAB9ANPSR1MEN1 | |
| SCHEMBL23609451 | 0.77 | ALDH1A1 (0.50) | CYP3A4ALDH1A1THRBALOX15RECQL | |
| SCHEMBL29973206 | 0.77 | ALDH1A1 (0.50) | CYP3A4ALDH1A1THRBALOX15RECQL | |
| SCHEMBL3040658 | 0.77 | KDR (0.52) | ALDH1A1ALOX15TDP1RAB9ANPSR1 | |
| SCHEMBL11511767 | 0.76 | CYP3A4 (0.77) | CYP3A4ALDH1A1THRBALOX15RECQL | |
| SCHEMBL2127369 | 0.75 | ALDH1A1 (0.70) | CYP3A4ALDH1A1THRBALOX15RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081800-A1 | ALPHA-2A ADRENERGIC RECEPTOR MODULATORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-05-11 | — | — | WO | disclosed |