Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 15/20 | 0.42 |
| ▸ | CNR1 | P21554 | 14/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25455345 | 0.90 | CNR2 (0.46) | HDAC8CNR2CNR1 | |
| SCHEMBL25455352 | 0.80 | CA12 (0.46) | HDAC8CNR2CNR1CA12CA1 | |
| SCHEMBL25455340 | 0.79 | ALB (0.48) | CNR2CNR1 | |
| SCHEMBL25456639 | 0.78 | CNR2 (0.48) | CNR2CNR1 | |
| SCHEMBL557650 | 0.77 | HDAC8 (0.44) | HDAC8CNR2CNR1 | |
| SCHEMBL712992 | 0.77 | HDAC1 (0.59) | HDAC8 | |
| SCHEMBL14544471 | 0.77 | HDAC1 (0.59) | HDAC8 | |
| SCHEMBL25456682 | 0.76 | CA1 (0.43) | CA12CA1CA2CA9 | |
| SCHEMBL30696861 | 0.76 | PLA2G4B (0.61) | HDAC8 | |
| SCHEMBL13008095 | 0.75 | HDAC8 (0.35) | HDAC8CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230145835-A1 | Modulators of Alpha-4-beta-7 Integrin and MAdCAM | QUANTUM INTELLIGENCE CORP. (KR) | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230145835-A1 | Modulators of Alpha-4-beta-7 Integrin and MAdCAM | ITGB7, ITGAM, ITGA4 | HDAC8 673/4885CNR2 3146/4885CNR1 2760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.