Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.68 |
| ▸ | NPC1 | O15118 | 5/20 | 0.68 |
| ▸ | RAB9A | P51151 | 5/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2541804 | 0.87 | RAB9A (0.74) | SMN1; SMN2NPC1RAB9ATDP1KDM4E | |
| SCHEMBL12238010 | 0.85 | NPC1 (0.77) | SMN1; SMN2NPC1RAB9ATDP1KDM4E | |
| SCHEMBL470778 | 0.82 | NPC1 (0.78) | SMN1; SMN2NPC1RAB9ATDP1KDM4E | |
| SCHEMBL29395943 | 0.82 | NPC1 (0.78) | SMN1; SMN2NPC1RAB9ATDP1KDM4E | |
| SCHEMBL12238007 | 0.75 | SMN1; SMN2 (0.86) | SMN1; SMN2NPC1RAB9ATDP1KDM4E | |
| SCHEMBL12238019 | 0.72 | RAB9A (0.60) | SMN1; SMN2NPC1RAB9ATDP1KDM4E | |
| SCHEMBL12238006 | 0.71 | MAPT (0.69) | SMN1; SMN2NPC1RAB9ATDP1KDM4E | |
| SCHEMBL2549638 | 0.70 | KDM4E (0.64) | SMN1; SMN2NPC1RAB9ATDP1KDM4E | |
| SCHEMBL16597288 | 0.69 | NISCH (0.54) | SMN1; SMN2NPC1RAB9ATDP1KDM4E | |
| SCHEMBL12238017 | 0.69 | MAPT (0.74) | SMN1; SMN2NPC1RAB9ATDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110262482-A1 | ANTI-VIRAL COMPOUNDS | Kineta, Inc. (US) | 2011-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110262482-A1 | ANTI-VIRAL COMPOUNDS | MAVS, EIF2AK2, IRF3 | SMN1; SMN2 2632/4885NPC1 1706/4885RAB9A 812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.