SCHEMBL25459798

SCHEMBL25459798

c1ccc(-c2ccc3c(c2)c2cccc4c5cc(-c6ccc7c8cccc9c%10ccccc%10n(c7c6)c98)ccc5n3c24)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSPO P30536 4/20 0.43
RXRA P19793 1/20 0.40
RXRB P28702 1/20 0.40
MAOB P27338 1/20 0.38
KDM4E B2RXH2 2/20 0.38
ALDH1A1 P00352 2/20 0.38
HPGD P15428 2/20 0.38
MEN1 O00255 1/20 0.38
POLB P06746 1/20 0.38
MAPT P10636 1/20 0.38
HTT P42858 1/20 0.38
KMT2A Q03164 1/20 0.38
DNM1 Q05193 2/20 0.37
LIMK1 P53667 1/20 0.36
NPY5R Q15761 1/20 0.35
CYP3A4 P08684 2/20 0.35
CYP2C9 P11712 2/20 0.35
HSD17B1 P14061 2/20 0.35
HSD17B2 P37059 2/20 0.35
CYP1A2 P05177 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25459799 1.00 TSPO (0.43) TSPORXRARXRBMAOBKDM4E
SCHEMBL24078818 1.00 TSPO (0.43) TSPORXRARXRBMAOBKDM4E
SCHEMBL24841125 1.00 TSPO (0.43) TSPORXRARXRBMAOBKDM4E
SCHEMBL24149766 0.98 TSPO (0.41) TSPORXRARXRBMAOBKDM4E
SCHEMBL23823734 0.98 TSPO (0.41) TSPORXRARXRBMAOBKDM4E
SCHEMBL23814087 0.97 TSPO (0.41) TSPORXRARXRBMAOBKDM4E
SCHEMBL25459796 0.97 TSPO (0.41) TSPORXRARXRBMAOBKDM4E
SCHEMBL23138556 0.95 TSPO (0.46) TSPORXRARXRBMAOBKDM4E
SCHEMBL23823559 0.95 KDM4E (0.41) TSPORXRARXRBMAOBKDM4E
SCHEMBL21717815 0.95 TSPO (0.46) TSPORXRARXRBMAOBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230255106-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2023-08-10 US disclosed
US-20230255106-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2023-08-10 US disclosed
US-20230172062-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2023-06-01 US disclosed
US-20230172062-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2023-06-01 US disclosed
US-20230157151-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2023-05-18 US disclosed
US-20230157151-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2023-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230172062-A1 ORGANIC ELECTROLUMINESCENT APPARATUS SLC29A1, SLC19A2, NUDT1 TSPO 314/4885RXRA 3641/4885RXRB 3588/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.