Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ENPEP | Q07075 | 13/20 | 0.45 |
| ▸ | CTSD | P07339 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31720964 | 0.94 | ENPEP (0.44) | ALDH1A1ENPEPCTSD | |
| SCHEMBL29382432 | 0.94 | ALDH1A1 (0.51) | ALDH1A1ENPEPL3MBTL1 | |
| SCHEMBL31720879 | 0.90 | ENPEP (0.48) | ALDH1A1ENPEPCTSD | |
| SCHEMBL30737597 | 0.90 | BACE1 (0.44) | ALDH1A1CTSDBACE1 | |
| SCHEMBL30390127 | 0.87 | PDCD1LG2 (0.49) | ALDH1A1ENPEP | |
| SCHEMBL30051564 | 0.87 | ALDH1A1 (0.47) | ALDH1A1ENPEPCTSDL3MBTL1 | |
| SCHEMBL29426362 | 0.86 | PDCD1LG2 (0.45) | ALDH1A1CTSDBACE1 | |
| SCHEMBL29531923 | 0.86 | PDCD1LG2 (0.45) | ALDH1A1CTSDBACE1 | |
| SCHEMBL31696945 | 0.86 | MME (0.49) | ENPEPCTSDBACE1 | |
| SCHEMBL30390006 | 0.85 | CD274 (0.52) | CTSDBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023079142-A2 | TARGETED LINEAR CONJUGATES COMPRISING POLYETHYLENEIMINE AND POLYETHYLENE GLYCOL AND POLYPLEXES COMPRISING THE SAME | TARGIMMUNE THERAPEUTICS AG (CH) | 2023-05-11 | — | — | WO | disclosed |