SCHEMBL25460468

SCHEMBL25460468

c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4c(-c5cccnc5)cccc4-c4ccccc4-c4nc(-c5ccccc5)nc(-c5ccccc5)n4)c3)n2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 3/20 0.43
TSHR P16473 4/20 0.42
SMN1; SMN2 Q16637 4/20 0.42
TP53 P04637 1/20 0.42
KMO O15229 1/20 0.42
ADORA3 P0DMS8 1/20 0.42
ALOX15 P16050 1/20 0.42
ADORA2A P29274 1/20 0.42
ADORA2B P29275 1/20 0.42
ADORA1 P30542 1/20 0.42
PDK2 Q15119 1/20 0.42
CYP19A1 P11511 2/20 0.42
ALDH1A1 P00352 3/20 0.42
MAPT P10636 2/20 0.42
CYP11B2 P19099 2/20 0.42
POLB P06746 1/20 0.42
GLA P06280 2/20 0.40
MEN1 O00255 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25462275 0.97 KMO (0.47) CYP11B1TSHRSMN1; SMN2TP53KMO
SCHEMBL25460872 0.97 KMO (0.43) CYP11B1TSHRSMN1; SMN2TP53KMO
SCHEMBL25460998 0.93 CYP11B1 (0.52) CYP11B1SMN1; SMN2CYP19A1ALDH1A1MAPT
SCHEMBL25461540 0.93 ALDH1A1 (0.42) CYP11B1TSHRSMN1; SMN2TP53ALDH1A1
SCHEMBL25460891 0.92 CYP19A1 (0.43) CYP11B1TSHRSMN1; SMN2TP53KMO
SCHEMBL25460090 0.88 SMN1; SMN2 (0.46) CYP11B1TSHRSMN1; SMN2TP53KMO
SCHEMBL25460585 0.88 CYP19A1 (0.46) CYP11B1TSHRSMN1; SMN2TP53KMO
SCHEMBL25461014 0.87 ALDH1A1 (0.48) CYP11B1TSHRSMN1; SMN2TP53CYP19A1
SCHEMBL25460732 0.86 CYP19A1 (0.47) CYP11B1SMN1; SMN2TP53KMOPDK2
SCHEMBL25460359 0.86 ALDH1A1 (0.50) CYP11B1TSHRSMN1; SMN2TP53KMO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023085637-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2023-05-19 WO disclosed