Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4097648 | 0.86 | SMN1; SMN2 (0.47) | L3MBTL1SMN1; SMN2KDM4ELMNAALDH1A1 | |
| SCHEMBL505194 | 0.79 | L3MBTL1 (0.52) | L3MBTL1SMN1; SMN2KDM4ELMNAALDH1A1 | |
| SCHEMBL12928720 | 0.79 | L3MBTL1 (0.52) | L3MBTL1SMN1; SMN2KDM4ELMNAALDH1A1 | |
| SCHEMBL504847 | 0.79 | PLCG1 (0.51) | L3MBTL1SMN1; SMN2KDM4EALDH1A1HDAC6 | |
| SCHEMBL8283520 | 0.78 | MAPT (0.52) | L3MBTL1SMN1; SMN2KDM4ELMNAALDH1A1 | |
| SCHEMBL25511737 | 0.78 | L3MBTL1 (0.50) | L3MBTL1SMN1; SMN2KDM4ELMNAALDH1A1 | |
| SCHEMBL25464082 | 0.77 | GRM5 (0.49) | SMN1; SMN2KDM4EALDH1A1NPY2RRAB9A | |
| SCHEMBL21241778 | 0.76 | LMNA (0.42) | SMN1; SMN2KDM4ELMNAALDH1A1NPC1 | |
| SCHEMBL4094548 | 0.76 | KDM4E (0.42) | SMN1; SMN2KDM4ELMNAALDH1A1NPY2R | |
| SCHEMBL2396377 | 0.75 | L3MBTL1 (0.47) | L3MBTL1SMN1; SMN2KDM4ELMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230151074-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | CARMOT THERAPEUTICS, INC. | 2023-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230151074-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | GIPR, GLP1R, GCGR | L3MBTL1 2173/4885SMN1; SMN2 1966/4885KDM4E 2921/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.