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Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL2546321

N.O=C(O)CCC(CC(=O)O)C(O)=S

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 12/20 0.64
▸ GRM3 Q14832 2/20 0.41
▸ NAALAD2 Q9Y3Q0 1/20 0.41
▸ TET2 Q6N021 3/20 0.39
▸ KDM4A O75164 2/20 0.39
▸ KDM4C Q9H3R0 2/20 0.39
▸ KDM2A Q9Y2K7 2/20 0.39
▸ TET3 O43151 1/20 0.39
▸ TDP1 Q9NUW8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1900382 0.98 FOLH1 (0.67) FOLH1GRM3NAALAD2TET2KDM4A
SCHEMBL28132387 0.95 FOLH1 (0.64) FOLH1GRM3NAALAD2TET2KDM4A
Ammonia Solution, Strong SCHEMBL2546314 0.89 FOLH1 (0.50) FOLH1GRM3NAALAD2TET2KDM4A
SCHEMBL1900376 0.86 FOLH1 (0.52) FOLH1GRM3NAALAD2TET2KDM4A
SCHEMBL8416810 0.84 FOLH1 (0.50) FOLH1
SCHEMBL8419050 0.83 FOLH1 (0.48) FOLH1
SCHEMBL8415664 0.81 LMNA (0.48) FOLH1
SCHEMBL4890978 0.80 FOLH1 (0.46) FOLH1TDP1
SCHEMBL27959736 0.79 FOLH1 (0.43) FOLH1TDP1
SCHEMBL28640 0.78 FOLH1 (1.00) FOLH1GRM3NAALAD2TET2KDM4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110258938-A1 Aluminum oxide particle and polishing composition containing the same FUJIMI INC. (JP) 2011-10-27 — — US disclosed
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