Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 4/20 | 0.44 |
| ▸ | ACKR3 | P25106 | 3/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25464167 | 0.75 | NPC1 (0.43) | MCHR1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL10132085 | 0.66 | SMN1; SMN2 (0.65) | SMYD3HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL12724987 | 0.66 | HPGD (0.51) | KMT2AHPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL16544523 | 0.66 | KDM1A (0.50) | KMT2AHPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22870418 | 0.65 | SMN1; SMN2 (0.50) | SMYD3HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL25464127 | 0.65 | NPC1 (0.42) | KMT2ANPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL30166184 | 0.64 | HPGD (0.50) | HDAC3HDAC1HDAC2HDAC6KMT2A | |
| SCHEMBL13657956 | 0.64 | LMNA (0.63) | SIGMAR1KMT2ANPC1RAB9A | |
| SCHEMBL531986 | 0.64 | MCHR1 (0.64) | MCHR1KMT2AHPGDNPC1RAB9A | |
| SCHEMBL13452475 | 0.63 | HDAC3 (0.44) | HDAC3HDAC1HDAC2HDAC6NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230151074-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | CARMOT THERAPEUTICS, INC. | 2023-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230151074-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | GIPR, GLP1R, GCGR | SMYD3 3485/4885ACKR3 519/4885SIGMAR1 253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.