Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.42 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.42 |
| ▸ | IDH2 | P48735 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25464213 | 0.83 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2CACNA1BHPGD | |
| SCHEMBL25464169 | 0.80 | LMNA (0.50) | NPC1RAB9ASMN1; SMN2CACNA1BHPGD | |
| SCHEMBL25460822 | 0.79 | AKR1C3 (0.44) | NPC1RAB9ACYP3A4CYP2C9AKR1C3 | |
| SCHEMBL25464108 | 0.78 | TAS1R3 (0.47) | NPC1RAB9ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL25463746 | 0.78 | KCNN4 (0.45) | NPC1RAB9AALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL25464127 | 0.77 | NPC1 (0.42) | NPC1RAB9ASMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL25464172 | 0.75 | SSTR4 (0.44) | NPC1RAB9ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL25464778 | 0.75 | CNR1 (0.36) | CACNA1BIDH2HPGDGAA | |
| SCHEMBL25464788 | 0.75 | TACR1 (0.42) | TAS1R3TAS1R1TAS1R2IDH2MCHR1 | |
| SCHEMBL25464147 | 0.74 | PDK1 (0.44) | NPC1RAB9ASMN1; SMN2TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230151074-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | CARMOT THERAPEUTICS, INC. | 2023-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230151074-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | GIPR, GLP1R, GCGR | NPC1 2460/4885RAB9A 658/4885SMN1; SMN2 1966/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.