Enoxolone

Enoxolone

SCHEMBL25465

CC1(C(=O)O)CCC2(C)CCC3(C)C(=CC(=O)C4C5(C)CCC(O)C(C)(C)C5CCC43C)C2C1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 10/20 1.00
HSD11B2 P80365 9/20 1.00
CES2 O00748 5/20 1.00
CES1 P23141 5/20 1.00
PTPN1 P18031 3/20 1.00
CYP3A4 P08684 2/20 1.00
MAPT P10636 2/20 1.00
ALOX5 P09917 2/20 1.00
MEN1 O00255 1/20 1.00
AKR1B10 O60218 1/20 1.00
LMNA P02545 1/20 1.00
PRKCH P24723 1/20 1.00
PTPN6 P29350 1/20 1.00
KMT2A Q03164 1/20 1.00
PTPN11 Q06124 1/20 1.00
SLCO1B3 Q9NPD5 1/20 1.00
SLCO1B1 Q9Y6L6 1/20 1.00
TSHR P16473 1/20 1.00
HSD17B1 P14061 1/20 0.76
HSD17B2 P37059 1/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Enoxolone SCHEMBL1878063 1.00 HSD11B1 (1.00) HSD11B1HSD11B2CES2CES1PTPN1
Enoxolone SCHEMBL8896296 1.00 HSD11B1 (1.00) HSD11B1HSD11B2CES2CES1PTPN1
Enoxolone SCHEMBL19248152 1.00 HSD11B1 (1.00) HSD11B1HSD11B2CES2CES1PTPN1
Enoxolone SCHEMBL13144257 1.00 HSD11B1 (1.00) HSD11B1HSD11B2CES2CES1PTPN1
Enoxolone SCHEMBL23016683 1.00 HSD11B1 (1.00) HSD11B1HSD11B2CES2CES1PTPN1
Enoxolone SCHEMBL2762928 1.00 HSD11B1 (1.00) HSD11B1HSD11B2CES2CES1PTPN1
Enoxolone SCHEMBL23252837 1.00 HSD11B1 (1.00) HSD11B1HSD11B2CES2CES1PTPN1
Enoxolone SCHEMBL12444056 1.00 HSD11B1 (1.00) HSD11B1HSD11B2CES2CES1PTPN1
Enoxolone SCHEMBL14071726 1.00 HSD11B1 (1.00) HSD11B1HSD11B2CES2CES1PTPN1
Enoxolone SCHEMBL12225660 1.00 HSD11B1 (1.00) HSD11B1HSD11B2CES2CES1PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 11317 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4529452-B1 DOSAGE FORMS FOR TOPICAL ADMINISTRATION OF PENTACYCLIC TRITERPENES GIULIANI SPA (IT) 2025-12-24 EP claimed
US-20250338841-A1 Dry Powdered Compositions and Methods and Uses Thereof NEOZYME INTERNATIONAL, INC. (US) 2025-11-06 US claimed
US-20250236979-A1 COMPOSITIONS FOR ELECTROWINNING ACID MIST SUPPRESSION W-TECH TECHNOLOGIES LTD. (CA) 2025-07-24 US claimed
US-12356985-B2 Dry powdered compositions and methods and uses thereof NEOZYME INTERNATIONAL, INC. (US) 2025-07-15 US claimed
US-20250170038-A1 DOSAGE FORMS FOR TOPICAL ADMINISTRATION OF PENTACYCLIC TRITERPENES GIULIANI S.P.A. (IT) 2025-05-29 US claimed
US-20250170082-A1 HPDL INHIBITORS AND USES THEREOF NEW YORK UNIVERSITY (US) 2025-05-29 US claimed
US-20250144021-A1 GEL FORMULATIONS FOR LOCAL DRUG RELEASE TECHNICAL UNIVERSITY OF DENMARK (DK) 2025-05-08 US claimed
WO-2025076059-A1 ROCAGLATE DERIVATIVES AND USES THEREOF TRUSTEES OF BOSTON UNIVERSITY (US) 2025-04-10 WO claimed
EP-4529452-A1 DOSAGE FORMS FOR TOPICAL ADMINISTRATION OF PENTACYCLIC TRITERPENES Giuliani S.p.A. (IT) 2025-04-02 EP claimed
EP-3943073-B1 BIODEGRADABLE POLYMER MICROPARTICLE CONTAINING STEROID-BASED DRUG AND PREPARATION METHOD THEREFOR REGENBIOTECH INC (KR) 2025-03-26 EP claimed
EP-0755675-B1 Dermatological and/or pharmaceutical composition, process of preparation and utilization OREAL (FR) 1997-09-17 EP claimed
EP-0792371-A1 COMBINATION METHOD FOR ACNE TREATMENT Merck & Co., Inc. (US) 1997-09-03 EP claimed
EP-0786999-A1 COMBINATION METHOD FOR ACNE TREATMENT Merck & Co., Inc. (US) 1997-08-06 EP claimed
US-5543417-A 5 Alpha-reductase inhibitor and at least one of an antibacterial agent, a keratolytic agent or an anti-inflammatory agent MERCK & CO., INC. (US) 1996-08-06 US claimed
WO-1996012487-A1 COMBINATION METHOD FOR ACNE TREATMENT MERCK & CO., INC. (US) 1996-05-02 WO claimed
WO-1996012817-A1 COMBINATION METHOD FOR ACNE TREATMENT MERCK & CO., INC. (US) 1996-05-02 WO claimed
CN-1096696-A A kind of preparation method of separating drunkenness dispelling tea LIANG KANGRU (CN) 1994-12-28 CN claimed
CN-1087526-A A Gan goes anticancer preparation prescription and technology UNIV BEIJING MEDICAL (CN) 1994-06-08 CN claimed
EP-0496520-A1 Novel bone acting agents MERCK & CO. INC. (US) 1992-07-29 EP claimed
EP-0197876-B1 THERAPEUTICAL COMPOSITION FOR USE IN DERMATOLOGY CONTAINING IMIDAZOLIDINYL UREA AS AN ACTIVE SUBSTANCE ANBEN (FR) 1990-07-11 EP claimed