Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 10/20 | 1.00 |
| ▸ | HSD11B2 | P80365 | 9/20 | 1.00 |
| ▸ | CES2 | O00748 | 5/20 | 1.00 |
| ▸ | CES1 | P23141 | 5/20 | 1.00 |
| ▸ | PTPN1 | P18031 | 3/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 2/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 1.00 |
| ▸ | ALOX5 | P09917 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | AKR1B10 | O60218 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | PRKCH | P24723 | 1/20 | 1.00 |
| ▸ | PTPN6 | P29350 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | PTPN11 | Q06124 | 1/20 | 1.00 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 1.00 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 1.00 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.76 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Enoxolone SCHEMBL15448799 | 1.00 | HSD11B1 (1.00) | HSD11B1HSD11B2CES2CES1PTPN1 | |
| Enoxolone SCHEMBL13382933 | 1.00 | HSD11B1 (1.00) | HSD11B1HSD11B2CES2CES1PTPN1 | |
| Enoxolone SCHEMBL2762655 | 1.00 | HSD11B1 (1.00) | HSD11B1HSD11B2CES2CES1PTPN1 | |
| Enoxolone SCHEMBL23016683 | 1.00 | HSD11B1 (1.00) | HSD11B1HSD11B2CES2CES1PTPN1 | |
| Enoxolone SCHEMBL25465 | 1.00 | HSD11B1 (1.00) | HSD11B1HSD11B2CES2CES1PTPN1 | |
| Enoxolone SCHEMBL23252837 | 1.00 | HSD11B1 (1.00) | HSD11B1HSD11B2CES2CES1PTPN1 | |
| Enoxolone SCHEMBL2762929 | 1.00 | HSD11B1 (1.00) | HSD11B1HSD11B2CES2CES1PTPN1 | |
| Enoxolone SCHEMBL6544340 | 1.00 | HSD11B1 (1.00) | HSD11B1HSD11B2CES2CES1PTPN1 | |
| Enoxolone SCHEMBL4916952 | 1.00 | HSD11B1 (1.00) | HSD11B1HSD11B2CES2CES1PTPN1 | |
| Enoxolone SCHEMBL231125 | 1.00 | HSD11B1 (1.00) | HSD11B1HSD11B2CES2CES1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023121486-A1 | COMPOSITIONS AND COMPOUNDS FOR TREATING COVID-19 | INTERNATIONAL PATENT HOLDINGS LLC (KN) | 2023-06-29 | — | — | WO | disclosed |
| US-20230190679-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2023-06-22 | — | — | US | disclosed |
| US-20220017471-A1 | FUNCTIONALITY INDEPENDENT LABELING OF ORGANIC COMPOUNDS | UNIV SHANGHAI TECHNOLOGY (CN) | 2022-01-20 | — | — | US | disclosed |
| US-20210315799-A1 | Composition for Promoting Differentiation or Proliferation of Human Adipose-Derived Stem Cell | LG HOUSEHOLD & HEALTH CARE LTD. (KR) | 2021-10-14 | — | — | US | disclosed |
| US-20140220063-A1 | VACCINE COMPOSITION | NITTO DENKO CORPORATION (JP) | 2014-08-07 | — | — | US | disclosed |
| US-20140220063-A1 | VACCINE COMPOSITION | NITTO DENKO CORPORATION (JP) | 2014-08-07 | — | — | US | disclosed |
| US-20130023487-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING INFECTION | INTERNATIONAL PATENT HOLDINGS LLC (KN) | 2013-01-24 | — | — | US | disclosed |
| US-20120190734-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING INFECTION | INTERNATIONAL PATENT HOLDINGS LLC (KN) | 2012-07-26 | — | — | US | disclosed |
| US-20080267948-A1 | Croos-B Structure Binding Compounds | CROSSBETA BIOSCIENCES B.V. (NL) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210315799-A1 | Composition for Promoting Differentiation or Proliferation of Human Adipose-Derived Stem Cell | LRBA, FABP4, ALOX15 | HSD11B1 456/4885HSD11B2 851/4885CES2 2423/4885 |
| US-20080267948-A1 | Croos-B Structure Binding Compounds | CACYBP, TBCB, MYCBP | HSD11B1 606/4885HSD11B2 684/4885CES2 819/4885 |
| US-20120190734-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING INFECTION | RPN2, LSS, CLIC4 | HSD11B1 2403/4885HSD11B2 1472/4885CES2 628/4885 |
| US-20220017471-A1 | FUNCTIONALITY INDEPENDENT LABELING OF ORGANIC COMPOUNDS | PAICS, PFAS, OTC | HSD11B1 3121/4885HSD11B2 2919/4885CES2 57/4885 |
| US-20230190679-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | SERPINC1, SERPINE1, SERPINH1 | HSD11B1 751/4885HSD11B2 675/4885CES2 4109/4885 |
| US-20130023487-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING INFECTION | RPN2, LSS, CLIC4 | HSD11B1 2403/4885HSD11B2 1472/4885CES2 628/4885 |
| US-20140220063-A1 | VACCINE COMPOSITION | MYD88, IRF3, CD14 | HSD11B1 1900/4885HSD11B2 2649/4885CES2 4644/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.