Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.40 |
| ▸ | GAK | O14976 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 2/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25468836 | 1.00 | HTR1A (0.51) | HTR1AADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL25465686 | 0.88 | HTR1A (0.47) | HTR1AADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL25467896 | 0.79 | HTR1A (0.52) | HTR1AADRA1DADRA1AADRA1BGAK | |
| SCHEMBL25465016 | 0.79 | HTR1A (0.52) | HTR1AADRA1DADRA1AADRA1BGAK | |
| SCHEMBL25465413 | 0.75 | HTR1A (0.55) | HTR1AADRA1DADRA1AADRA1BGAK | |
| SCHEMBL26864598 | 0.75 | IKBKB (0.38) | ALDH1A1SLC40A1GAKHTT | |
| SCHEMBL26862953 | 0.75 | IKBKB (0.38) | ALDH1A1SLC40A1GAKHTT | |
| SCHEMBL30666120 | 0.74 | BRAF (0.36) | ALDH1A1GAKHTTGAAFBP1 | |
| SCHEMBL26656440 | 0.74 | BRAF (0.36) | ALDH1A1GAKHTTGAAFBP1 | |
| SCHEMBL26864188 | 0.74 | BRAF (0.36) | ALDH1A1GAKHTTGAAFBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086638-A1 | ENPP1 MODULATORS AND USES THEREOF | Vir Biotechnology, Inc. (US) | 2023-05-19 | — | — | WO | disclosed |