Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.37 |
| ▸ | GAK | O14976 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | AURKA | O14965 | 2/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25468836 | 0.88 | HTR1A (0.51) | HTR1AADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL25465017 | 0.88 | HTR1A (0.51) | HTR1AADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL30666120 | 0.87 | BRAF (0.36) | ALDH1A1GAKGAAHTTFBP1 | |
| SCHEMBL26656440 | 0.87 | BRAF (0.36) | ALDH1A1GAKGAAHTTFBP1 | |
| SCHEMBL26864188 | 0.87 | BRAF (0.36) | ALDH1A1GAKGAAHTTFBP1 | |
| SCHEMBL26865331 | 0.87 | BRAF (0.36) | ALDH1A1GAKGAAHTTFBP1 | |
| SCHEMBL25468134 | 0.86 | EGFR (0.47) | GAKAURKAAURKB | |
| SCHEMBL25468137 | 0.86 | EGFR (0.47) | GAKAURKAAURKB | |
| SCHEMBL25465601 | 0.84 | EGFR (0.54) | GAKPDGFRA | |
| SCHEMBL25464971 | 0.84 | EGFR (0.54) | GAKPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086638-A1 | ENPP1 MODULATORS AND USES THEREOF | Vir Biotechnology, Inc. (US) | 2023-05-19 | — | — | WO | disclosed |