Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | PLAT | P00750 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | VCP | P55072 | 2/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL368411 | 0.89 | — | — | |
| SCHEMBL10729681 | 0.89 | ALDH1A1 (0.52) | LMNAKMT2ATDP1ALDH1A1TSHR | |
| SCHEMBL19605699 | 0.81 | TDP1 (0.45) | LMNAKMT2ATDP1ALDH1A1TSHR | |
| SCHEMBL30900511 | 0.81 | PLG (0.42) | PLGPLATLMNAKMT2ATDP1 | |
| SCHEMBL14514537 | 0.81 | EPHX1 (0.52) | LMNAKMT2ATDP1ALDH1A1TSHR | |
| SCHEMBL19951575 | 0.81 | KMT2A (0.43) | PLGPLATLMNAKMT2ATDP1 | |
| SCHEMBL16054834 | 0.81 | LMNA (0.44) | PLGPLATLMNAKMT2ATDP1 | |
| SCHEMBL16054840 | 0.81 | LMNA (0.44) | PLGPLATLMNAKMT2ATDP1 | |
| SCHEMBL16054838 | 0.81 | LMNA (0.44) | PLGPLATLMNAKMT2ATDP1 | |
| SCHEMBL16054837 | 0.81 | LMNA (0.44) | PLGPLATLMNAKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086028-A2 | ALLENAMIDE LINKERS FOR ANTIBODY-DRUG CONJUGATE | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2023-05-19 | — | — | WO | disclosed |