Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | F13A1 | P00488 | 1/20 | 0.31 |
| ▸ | TGM1 | P22735 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAK | O14976 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25181526 | 0.86 | TDP1 (0.30) | TDP1 | |
| SCHEMBL21731479 | 0.85 | MAP3K7 (0.34) | KMT2AALDH1A1LMNATDP1TSHR | |
| SCHEMBL21731542 | 0.83 | KMT2A (0.36) | KMT2AALDH1A1MGLLSMN1; SMN2MEN1 | |
| SCHEMBL21731540 | 0.83 | MAP3K7 (0.33) | KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL180930 | 0.80 | TDP1 (0.33) | KMT2AALDH1A1LMNATDP1MGLL | |
| SCHEMBL21538842 | 0.78 | MEN1 (0.33) | KMT2AALDH1A1TSHRMGLLMEN1 | |
| SCHEMBL17776136 | 0.78 | MGLL (0.33) | KMT2ATDP1MGLLSMN1; SMN2 | |
| SCHEMBL855021 | 0.78 | MGLL (0.33) | KMT2ATDP1MGLLSMN1; SMN2 | |
| SCHEMBL18751703 | 0.78 | MGLL (0.33) | KMT2ATDP1MGLLSMN1; SMN2 | |
| SCHEMBL17776064 | 0.78 | MGLL (0.33) | KMT2ATDP1MGLLSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086028-A2 | ALLENAMIDE LINKERS FOR ANTIBODY-DRUG CONJUGATE | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2023-05-19 | — | — | WO | disclosed |