Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25465669 | 1.00 | OPRM1 (0.33) | OPRM1OPRK1KMT2A | |
| SCHEMBL24811600 | 0.79 | KMT2A (0.39) | OPRM1OPRK1KMT2A | |
| SCHEMBL19424166 | 0.78 | OPRM1 (0.41) | OPRM1OPRK1KMT2A | |
| SCHEMBL13067273 | 0.78 | OPRM1 (0.41) | OPRM1OPRK1KMT2A | |
| SCHEMBL17531148 | 0.77 | OPRM1 (0.32) | OPRM1OPRK1KMT2A | |
| SCHEMBL25001367 | 0.76 | KMT2A (0.32) | OPRM1OPRK1KMT2A | |
| SCHEMBL25082216 | 0.76 | KMT2A (0.36) | OPRM1OPRK1KMT2A | |
| SCHEMBL19801472 | 0.74 | KMT2A (0.39) | OPRM1OPRK1KMT2A | |
| SCHEMBL25018501 | 0.74 | OPRM1 (0.30) | OPRM1OPRK1 | |
| SCHEMBL12927442 | 0.71 | KMT2A (0.32) | OPRM1OPRK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4397661-A1 | COMPOUND FOR DEGRADATION OF BCL-2 FAMILY PROTEINS AND MEDICAL APPLICATION THEREOF | Xizang Haisco Pharmaceutical Co., Ltd. (CN) | 2024-07-10 | — | — | EP | disclosed |
| EP-4180432-A1 | COMPOUND HAVING BTK KINASE DEGRADING ACTIVITY, AND PREPARATION METHOD AND PHARMACEUTICAL USE THEREFOR | Sichuan Haisco Pharmaceutical Co., Ltd. (CN) | 2023-05-17 | — | — | EP | disclosed |