Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13067273 | 1.00 | OPRM1 (0.41) | OPRM1OPRK1KMT2ALMNA | |
| SCHEMBL25465671 | 0.78 | OPRM1 (0.33) | OPRM1OPRK1KMT2A | |
| SCHEMBL25465669 | 0.78 | OPRM1 (0.33) | OPRM1OPRK1KMT2A | |
| SCHEMBL19417140 | 0.76 | OPRM1 (0.39) | OPRM1OPRK1KMT2ALMNA | |
| SCHEMBL21181787 | 0.76 | OPRM1 (0.39) | OPRM1OPRK1KMT2ALMNA | |
| Nitrobenzene SCHEMBL27814899 | 0.76 | ALDH1A1 (0.46) | OPRM1OPRK1KMT2ALMNA | |
| SCHEMBL19725924 | 0.75 | OPRM1 (0.38) | OPRM1OPRK1KMT2ALMNA | |
| SCHEMBL22148186 | 0.75 | OPRM1 (0.38) | OPRM1OPRK1KMT2ALMNA | |
| SCHEMBL25820270 | 0.75 | OPRM1 (0.38) | OPRM1OPRK1KMT2ALMNA | |
| SCHEMBL14184047 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170283398-A1 | 2-AMINOPYRIMIDINE COMPOUND AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2017-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170283398-A1 | 2-AMINOPYRIMIDINE COMPOUND AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | EGFR, ERBB2, IGF1R | OPRM1 2554/4885OPRK1 2732/4885KMT2A 1688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.