SCHEMBL25466527

SCHEMBL25466527

CC[C@@H]1NC(=O)[C@H](CCN)NC(=O)[C@H](CCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CCN)NC(=O)[C@@H](NC(=O)[C@H](CCN)NC(=O)C[C@@H](C)O)CCNC1=O

nearest known ligand 0.67

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ KDM1A O60341 3/20 0.67
▸ RCOR1 Q9UKL0 2/20 0.67
▸ TERF2 Q15554 2/20 0.43
▸ PSMB5 P28074 4/20 0.40
▸ PSMB2 P49721 3/20 0.40
▸ MC4R P32245 2/20 0.39
▸ MC1R Q01726 2/20 0.39
▸ IDE P14735 1/20 0.39
▸ TEAD4 Q15561 1/20 0.38
▸ TEAD3 Q99594 1/20 0.38
▸ GHSR Q92847 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25455642 0.92 KDM1A (0.77) KDM1ARCOR1TERF2
SCHEMBL25455822 0.92 KDM1A (0.77) KDM1ARCOR1TERF2
SCHEMBL20366251 0.92 KDM1A (0.77) KDM1ARCOR1TERF2
SCHEMBL25466596 0.92 KDM1A (0.77) KDM1ARCOR1TERF2
SCHEMBL25465478 0.92 KDM1A (0.69) KDM1ARCOR1TERF2PSMB5PSMB2
SCHEMBL24270420 0.90 KDM1A (0.70) KDM1ARCOR1TERF2PSMB5PSMB2
SCHEMBL22677698 0.90 KDM1A (0.68) KDM1ARCOR1TERF2PSMB5PSMB2
SCHEMBL22677633 0.90 KDM1A (0.68) KDM1ARCOR1TERF2PSMB5PSMB2
SCHEMBL22677681 0.90 KDM1A (0.70) KDM1ARCOR1TERF2PSMB5PSMB2
SCHEMBL24270410 0.90 KDM1A (0.70) KDM1ARCOR1TERF2PSMB5PSMB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230141981-A1 NOVEL COMPOUNDS AND COMPOSITION FOR TARGETED THERAPY OF KIDNEY-ASSOCIATED CANCERS Shanghai MICURX Pharmaceuticals Co., Ltd. (CN) 2023-05-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230141981-A1 NOVEL COMPOUNDS AND COMPOSITION FOR TARGETED THERAPY OF KIDNEY-ASSOCIATED CANCERS GLS, ATP6V1B1, KRAS KDM1A 3592/4885RCOR1 4682/4885TERF2 3270/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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