SCHEMBL254671

SCHEMBL254671

Oc1ccc(-c2ccc(OCc3ccccc3)cc2)cc1

nearest known ligand 0.88

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.88
CYP1A2 P05177 1/20 0.88
PTGS1 P23219 1/20 0.88
SLC6A2 P23975 1/20 0.88
CYP2C19 P33261 1/20 0.88
PTGS2 P35354 1/20 0.88
SLC6A3 Q01959 1/20 0.88
HIF1A Q16665 1/20 0.88
HDAC6 Q9UBN7 1/20 0.88
GAA P10253 3/20 0.63
MAPT P10636 3/20 0.63
MEN1 O00255 2/20 0.63
BLM P54132 2/20 0.63
KMT2A Q03164 2/20 0.63
TP53 P04637 1/20 0.63
ATM Q13315 1/20 0.63
MCL1 Q07820 1/20 0.62
GSTP1 P09211 2/20 0.61
MAOB P27338 4/20 0.60
L3MBTL1 Q9Y468 2/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6059234 0.98 LMNA (0.85) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL4506574 0.94 LMNA (0.78) LMNACYP1A2PTGS1SLC6A2CYP2C19
Monobenzone SCHEMBL35631 0.94 LMNA (1.00) LMNACYP1A2PTGS1SLC6A2CYP2C19
Monobenzone SCHEMBL8450838 0.94 LMNA (1.00) LMNACYP1A2PTGS1SLC6A2CYP2C19
Monobenzone SCHEMBL1903511 0.94 LMNA (1.00) LMNACYP1A2PTGS1SLC6A2CYP2C19
Monobenzone SCHEMBL11272996 0.94 LMNA (1.00) LMNACYP1A2PTGS1SLC6A2CYP2C19
Sulfur Dioxide SCHEMBL28532111 0.93 LMNA (0.76) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL27980945 0.92 LMNA (0.74) LMNACYP1A2PTGS1SLC6A2CYP2C19
Monobenzone SCHEMBL10803321 0.92 LMNA (0.96) LMNACYP1A2PTGS1SLC6A2CYP2C19
Monobenzone SCHEMBL10972560 0.92 LMNA (0.96) LMNACYP1A2PTGS1SLC6A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-11092426-A None JP disclosed
JP-60079996-A None JP disclosed
CN-119053452-A Thermosensitive recording medium 王子控股株式会社 2024-11-29 CN disclosed
CN-118973826-A Thermosensitive recording medium 王子控股株式会社 2024-11-15 CN disclosed
CN-118695949-A Thermosensitive recording medium 株式会社理光 2024-09-24 CN disclosed
US-11999892-B2 Liquid crystal composition, liquid crystal display element and compound DIC CORPORATION (JP) 2024-06-04 US disclosed
CN-117957123-A Thermosensitive recording medium 王子控股株式会社 2024-04-30 CN disclosed
CN-112533967-B Oil-in-water droplet type emulsion of active energy ray-curable resin composition and thermosensitive recording material 日本化药株式会社 2023-09-15 CN disclosed
US-11639327-B2 Polymerizable compound, and liquid crystal composition and liquid crystal display device using the same DIC CORPORATION (JP) 2023-05-02 US disclosed
US-11639327-B2 Polymerizable compound, and liquid crystal composition and liquid crystal display device using the same DIC CORPORATION (JP) 2023-05-02 US disclosed
WO-1992020331-A1 RECEPTOR LIGANDS KAROBIO AKTIEBOLAG (SE) 1992-11-26 WO disclosed
US-5166403-A Liquid crystals SHOWA DENKO K.K. (JP) 1992-11-24 US disclosed
EP-0225728-B1 LIQUID CRYSTALLINE CARBONIC ACID ESTER AND LIQUID CRYSTAL COMPOSITION CONTAINING SAME Chisso Corporation (JP) 1991-07-03 EP disclosed
EP-0428720-A1 OPTICALLY ACTIVE COMPOUNDS AND LIQUID CRYSTAL PHASE. MERCK PATENT GMBH (DE) 1991-05-29 EP disclosed
WO-1990013611-A2 OPTICALLY ACTIVE COMPOUNDS AND LIQUID CRYSTAL PHASE MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1990-11-15 WO disclosed
US-4886619-A TILTED OR LATENT TILTED MESOPHASES; BLENDS; FERROELECTRIC DEVICE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-12-12 US disclosed
US-4759869-A Carbonic acid ester containing assymetrical carbon atom and benzene rings CHISSO CORPORATION (JP) 1988-07-26 US disclosed
EP-0256303-A2 Liquid crystal compounds having fluorine-containing core POLAROID CORPORATION (US) 1988-02-24 EP disclosed
EP-0225728-A2 Liquid crystalline carbonic acid ester and liquid crystal composition containing same Chisso Corporation (JP) 1987-06-16 EP disclosed
JP-S6079996-A THERMAL RECORDING PAPER UENO SEIYAKU OYO KENKYUSHO:KK 1985-05-07 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11639327-B2 Polymerizable compound, and liquid crystal composition and liquid crystal display device using the same SKP1, PKN1, KTN1 LMNA 1852/4885CYP1A2 3295/4885PTGS1 2252/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.