Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26743104 | 0.89 | ALDH1A1 (0.41) | LMNAALDH1A1KDM4EPOLBSMN1; SMN2 | |
| SCHEMBL24185415 | 0.86 | ALDH1A1 (0.44) | LMNAALDH1A1KDM4EPOLBL3MBTL3 | |
| SCHEMBL12038511 | 0.86 | KDM4E (0.38) | LMNAALDH1A1KDM4EALOX15POLB | |
| SCHEMBL24480309 | 0.85 | ALDH1A1 (0.39) | LMNAALDH1A1KDM4EPOLBSMN1; SMN2 | |
| SCHEMBL25468012 | 0.84 | LMNA (0.40) | LMNAALDH1A1KDM4EALOX15POLB | |
| SCHEMBL12038515 | 0.83 | ALDH1A1 (0.35) | LMNAALDH1A1KDM4EL3MBTL3L3MBTL1 | |
| SCHEMBL18136222 | 0.83 | — | — | |
| SCHEMBL26475395 | 0.82 | ALDH1A1 (0.44) | LMNAALDH1A1KDM4EALOX15POLB | |
| SCHEMBL24185788 | 0.82 | KDM4E (0.43) | LMNAALDH1A1KDM4EALOX15POLB | |
| SCHEMBL26475374 | 0.82 | KDM4E (0.36) | LMNAALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4180432-A1 | COMPOUND HAVING BTK KINASE DEGRADING ACTIVITY, AND PREPARATION METHOD AND PHARMACEUTICAL USE THEREFOR | Sichuan Haisco Pharmaceutical Co., Ltd. (CN) | 2023-05-17 | — | — | EP | disclosed |