Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | P4HTM | Q9NXG6 | 5/20 | 0.47 |
| ▸ | P4HA1 | P13674 | 2/20 | 0.47 |
| ▸ | MIF | P14174 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LDHA | P00338 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31359466 | 0.87 | P4HTM (0.59) | MAP4K4P4HTMP4HA1MIFKDM4E | |
| SCHEMBL249720 | 0.87 | P4HTM (0.59) | MAP4K4P4HTMP4HA1MIFKDM4E | |
| Hydrochloric Acid SCHEMBL21485420 | 0.85 | P4HTM (0.57) | MAP4K4P4HTMP4HA1MIFKDM4E | |
| SCHEMBL254682 | 0.84 | MAP4K4 (0.55) | MAP4K4P4HTMP4HA1MIFKDM4E | |
| Methylamine SCHEMBL3235636 | 0.83 | P4HTM (0.55) | MAP4K4P4HTMP4HA1MIFKDM4E | |
| SCHEMBL7942053 | 0.81 | MAPK1 (0.53) | KDM4EHIF1AL3MBTL1SMN1; SMN2MAPK1 | |
| SCHEMBL4558391 | 0.79 | MAP4K4 (0.55) | MAP4K4P4HTMP4HA1MIFKDM4E | |
| SCHEMBL13731115 | 0.79 | P4HTM (0.64) | MAP4K4P4HTMP4HA1MIFKDM4E | |
| SCHEMBL30337692 | 0.77 | METAP2 (0.45) | KDM4EALDH1A1SMN1; SMN2KMT2ATDP1 | |
| SCHEMBL8974216 | 0.77 | METAP2 (0.45) | KDM4EALDH1A1SMN1; SMN2KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010011914-A1 | TRPV4 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2010-01-28 | — | — | WO | disclosed |