SCHEMBL2547243

SCHEMBL2547243

O=C(O)C(Cl)(Cl)c1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.65
TSHR P16473 4/20 0.50
CYP2D6 P10635 1/20 0.43
MAPT P10636 1/20 0.43
KMT2A Q03164 1/20 0.43
ALDH1A1 P00352 2/20 0.42
KCNN4 O15554 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
HIF1A Q16665 1/20 0.41
KEAP1 Q14145 1/20 0.41
NFE2L2 Q16236 1/20 0.41
HDAC3 O15379 1/20 0.40
HDAC4 P56524 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC7 Q8WUI4 1/20 0.40
HDAC2 Q92769 1/20 0.40
HDAC10 Q969S8 1/20 0.40
HDAC11 Q96DB2 1/20 0.40
HDAC8 Q9BY41 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29177580 0.91 CYP1A2 (0.56) CYP1A2TSHRCYP2D6MAPTKMT2A
SCHEMBL11692512 0.85 CYP1A2 (0.54) CYP1A2TSHRCYP2D6MAPTKMT2A
SCHEMBL7987418 0.84 CYP1A2 (0.58) CYP1A2TSHRCYP2D6MAPTKMT2A
SCHEMBL3086830 0.82 CYP1A2 (0.56) CYP1A2TSHRCYP2D6MAPTKMT2A
SCHEMBL6961047 0.82 CYP1A2 (0.56) CYP1A2TSHRCYP2D6MAPTKMT2A
SCHEMBL8818467 0.82 CYP1A2 (0.56) CYP1A2TSHRCYP2D6MAPTKMT2A
SCHEMBL27838434 0.80 MIF (0.57) CYP1A2TSHRCYP2D6MAPTKMT2A
SCHEMBL9792726 0.80 CYP1A2 (0.43) CYP1A2TSHRMAPTKMT2AALDH1A1
SCHEMBL8984631 0.80 CYP1A2 (0.54) CYP1A2TSHRCYP2D6MAPTKMT2A
SCHEMBL4556174 0.80 MAPT (0.56) CYP1A2TSHRCYP2D6MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4685176-A1 2-COMPONENT FOAMS BASED ON ACETYLACETONATE AND AMINES Henkel AG & Co. KGaA (DE) 2026-01-28 EP claimed
US-12528974-B2 Polishing slurry composition KCTECH CO., LTD. (KR) 2026-01-20 US claimed
US-20240158667-A1 POLISHING SLURRY COMPOSITION KCTECH CO., LTD. (KR) 2024-05-16 US claimed
WO-2022231115-A1 POLISHING SLURRY COMPOSITION 주식회사 케이씨텍 2022-11-03 WO claimed
EP-1332167-B1 PROCESS TO IMPROVE POLYURETHANE FOAM PERFORMANCE GEN ELECTRIC (US) 2008-09-17 EP claimed
EP-1018525-B1 Process for preparing polyurethane foam GEN ELECTRIC (US) 2006-08-30 EP claimed
EP-1362073-B1 PROCESS TO ENHANCE POLYURETHANE FOAM PERFORMANCE GEN ELECTRIC (US) 2005-12-14 EP claimed
EP-1534766-A1 PROCESS FOR PREPARING POLYURETHANE FOAM GENERAL ELECTRIC COMPANY (US) 2005-06-01 EP claimed
CN-1198862-C Process for producing polyurethane foam plastics CK THE WHITAKER CORP (US) 2005-04-27 CN claimed
US-6818675-B2 USING REACTION PRODUCT OF TERTIARY AMINE AND ACID AS POLYMERIZATION CATALYST GENERAL ELECTRIC COMPANY 2004-11-16 US claimed
EP-1332167-A2 PROCESS TO IMPROVE POLYURETHANE FOAM PERFORMANCE Crompton Corporation (US) 2003-08-06 EP claimed
WO-2002066531-A2 PROCESS TO ENHANCE POLYURETHANE FOAM PERFORMANCE CROMPTON CORPORATION (US) 2002-08-29 WO claimed
US-6423756-B1 USING CATALYST SYSTEM CROMPTON CORPORATION 2002-07-23 US claimed
WO-2002048229-A2 PROCESS TO IMPROVE POLYURETHANE FOAM PERFORMANCE CROMPTON CORPORATION (US) 2002-06-20 WO claimed
US-6395796-B1 CONDENSATION OF POLYISOCYANATE AND POLYOL USING DELAYED ACTION AMINE CATALYST FORMED BY REACTION OF HALOCARBOXYLIC ACID AND TERTIARY AMINE CROMPTON CORPORATION 2002-05-28 US claimed
US-6387972-B1 MIXTURE CONTAINING TERTIARY AMINE ADJUVANT CROMPTON CORPORATION 2002-05-14 US claimed
CN-1269372-A Process for producing polyurethane foam plastics CK THE WHITAKER CORP (US) 2000-10-11 CN claimed
EP-1018525-A1 Process for preparing polyurethane foam CK WITCO CORPORATION (US) 2000-07-12 EP claimed
US-4486576-A NICKEL-CATALYZED COUPLING UNION CARBIDE CORPORATION (US) 1984-12-04 US claimed
EP-0095042-A1 Aromatic coating materials from aryl polyhalides UNION CARBIDE CORPORATION (US) 1983-11-30 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12528974-B2 Polishing slurry composition ACP1, CA1, CA11 CYP1A2 4577/4885TSHR 4253/4885CYP2D6 4874/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.