Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 3/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2547243 | 0.82 | CYP1A2 (0.65) | CYP1A2TSHRMAPTKMT2AKCNN4 | |
| SCHEMBL7987418 | 0.82 | CYP1A2 (0.58) | CYP1A2TSHRMAPTKMT2AKCNN4 | |
| SCHEMBL8818467 | 0.80 | CYP1A2 (0.56) | CYP1A2TSHRMAPTKMT2AKCNN4 | |
| SCHEMBL1321231 | 0.80 | CYP1A2 (0.70) | CYP1A2TSHRMAPTKMT2AKCNN4 | |
| SCHEMBL6961047 | 0.80 | CYP1A2 (0.56) | CYP1A2TSHRMAPTKMT2AKCNN4 | |
| SCHEMBL659707 | 0.79 | TSHR (0.52) | CYP1A2TSHRMAPTKMT2AKCNN4 | |
| SCHEMBL8984631 | 0.78 | CYP1A2 (0.54) | CYP1A2TSHRMAPTKMT2AKCNN4 | |
| SCHEMBL4556174 | 0.78 | MAPT (0.56) | CYP1A2TSHRMAPTKMT2AKCNN4 | |
| SCHEMBL27651968 | 0.78 | CYP1A2 (0.54) | CYP1A2TSHRMAPTKMT2AKCNN4 | |
| SCHEMBL4946780 | 0.78 | CYP1A2 (0.54) | CYP1A2TSHRMAPTKMT2AKCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106133004-B | Catalyst component for olefin polymerization | 巴塞尔聚烯烃意大利有限公司 | 2019-05-07 | — | — | CN | disclosed |
| CN-108863774-A | A kind of 2,4 dichloro benzene chloroacetic chloride synthetic method | 石家庄市绿丰化工有限公司 | 2018-11-23 | — | — | CN | disclosed |
| CN-108658913-A | A kind of method of synthetic pesticide Envidor key intermediate | 石家庄市绿丰化工有限公司 | 2018-10-16 | — | — | CN | disclosed |
| CN-101951770-A | Hcv protease inhibitors and uses thereof | AVILA THERAPEUTICS INC | 2011-01-19 | — | — | CN | disclosed |
| US-7799952-B2 | Stereoselective method for the production of (R)-Dimepranol | RATIOPHARM GMBH (DE) | 2010-09-21 | — | — | US | disclosed |
| US-20090149677-A1 | Stereoselective Method for the Production of (R)-Dimepranol | RATIOPHARM GMBH (DE) | 2009-06-11 | — | — | US | disclosed |
| US-7507827-B2 | Stereoselective method for the production of Clopidogrel | RATIOPHARM GMBH (DE) | 2009-03-24 | — | — | US | disclosed |
| JP-2008184411-A | METHOD FOR PRODUCING 2,2-DIFLUORO-PHENYLACETOACETATE | CENTRAL GLASS CO LTD | 2008-08-14 | — | — | JP | disclosed |
| JP-2008184410-A | METHOD FOR PRODUCING 2,2-DIFLUORO-PHENYLACETOACETATE | CENTRAL GLASS CO LTD | 2008-08-14 | — | — | JP | disclosed |
| EP-1737868-B1 | STEREOSELECTIVE METHOD FOR THE PRODUCTION OF CLOPIDOGREL | RATIOPHARM GMBH (DE) | 2008-02-27 | — | — | EP | disclosed |
| EP-0330360-A1 | 1,2,3,4-Tetrahydroisoquinolines, processes for their preparation, and their use as kappa-receptor agonists | SmithKline Beecham Farmaceutici S.p.A. (IT) | 1989-08-30 | — | — | EP | disclosed |
| EP-0325406-A2 | Diamine compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-07-26 | — | — | EP | disclosed |
| EP-0189774-B1 | PROCESS FOR PRODUCTION OF N,N-DISUBSTITUTED CARBOXYLIC ACID AMIDES | TOKUYAMA SODA KABUSHIKI KAISHA (JP) | 1989-04-12 | — | — | EP | disclosed |
| EP-0260555-A1 | Benzo-fused cycloalkane and oxa- and thia-, cycloalkane trans-1,2-diamine derivatives | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1988-03-23 | — | — | EP | disclosed |
| US-4691052-A | Process for the preparation of pyrethroid acids | S.C. JOHNSON & SON, INC. (US) | 1987-09-01 | — | — | US | disclosed |
| EP-0189774-A1 | Process for production of N,N-disubstituted carboxylic acid amides | TOKUYAMA SODA KABUSHIKI KAISHA (JP) | 1986-08-06 | — | — | EP | disclosed |
| CN-86100282-A | N, the manufacture method of N-two generations carboxylic acyloxy amine | — | 1986-07-16 | — | — | CN | disclosed |
| EP-0116639-A4 | ACYL GUANIDINES. | RORER INTERNAT OVERSEAS INC (US) | 1985-09-25 | — | — | EP | disclosed |
| EP-0116639-A1 | ACYL GUANIDINES | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1984-08-29 | — | — | EP | disclosed |
| WO-1984000875-A1 | ACYL GUANIDINES | RORER INT OVERSEAS (US) | 1984-03-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149677-A1 | Stereoselective Method for the Production of (R)-Dimepranol | ADH5, ADH1A, ADH1C | CYP1A2 26/4885TSHR 1515/4885MAPT 3745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.