SCHEMBL25474368

SCHEMBL25474368

Cc1cc(-c2ccc3c(c2)CCC3Oc2cccc([C@@H](CP(C)(C)=O)C3CC3)c2)c(F)cn1

nearest known ligand 0.57

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 17/20 0.57
RET P07949 2/20 0.37
GFRA3 O60609 2/20 0.37
GFRA2 O00451 1/20 0.35
GFRA1 P56159 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25474727 0.91 FFAR1 (0.69) FFAR1
SCHEMBL25474370 0.88 FFAR1 (0.64) FFAR1
SCHEMBL25474728 0.85 FFAR1 (0.77) FFAR1
SCHEMBL25475835 0.85 FFAR1 (0.69) FFAR1
SCHEMBL25475836 0.79 FFAR1 (0.77) FFAR1
SCHEMBL18101343 0.75 FFAR1 (0.83) FFAR1
SCHEMBL25474512 0.73 FFAR1 (0.41) FFAR1
SCHEMBL18101337 0.73 FFAR1 (0.89) FFAR1
SCHEMBL25474322 0.73 FFAR1 (0.46) FFAR1
SCHEMBL25474329 0.73 FFAR1 (0.46) FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230151037-A1 GPR40 AGONISTS KALLYOPE, INC. 2023-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230151037-A1 GPR40 AGONISTS GPR119, GPR65, GLP1R FFAR1 10/4885RET 1106/4885GFRA3 722/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.