Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 3/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.50 |
| ▸ | NOS3 | P29474 | 2/20 | 0.43 |
| ▸ | NOS2 | P35228 | 2/20 | 0.43 |
| ▸ | NOS1 | P29475 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32683505 | 1.00 | ADORA1 (0.50) | ADORA1ADORA2ANOS3NOS2NOS1 | |
| SCHEMBL31207340 | 0.81 | ADORA1 (0.46) | ADORA1ADORA2ACA5AGAAKMT2A | |
| SCHEMBL11975949 | 0.80 | HSD17B10 (0.38) | ADORA1ADORA2AGAAKMT2ALMNA | |
| SCHEMBL7926347 | 0.79 | ADORA1 (0.48) | ADORA1ADORA2AGAAKMT2AKDM4E | |
| SCHEMBL16752186 | 0.76 | ADORA1 (0.39) | ADORA1ADORA2AGAAKMT2ATSHR | |
| SCHEMBL3150981 | 0.76 | ADORA2A (0.38) | ADORA1ADORA2AGAAKMT2ATSHR | |
| SCHEMBL20916782 | 0.74 | MAPK13 (0.47) | ADORA1ADORA2ACA5AMAPK13MAPK12 | |
| SCHEMBL31512175 | 0.73 | CLK1 (0.46) | ADORA1ADORA2AKMT2ANPC1RAB9A | |
| SCHEMBL4565224 | 0.72 | ADORA1 (0.42) | ADORA1ADORA2ACA5AGABRPGABRD | |
| SCHEMBL493663 | 0.71 | ADORA1 (0.41) | ADORA1ADORA2ACA5AGABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4426688-B1 | DDR1 AND DDR2 INHIBITORS FOR THE TREATEMENT OF CANCER AND FIBROTIC DISEASES | REDX PHARMA LTD (GB) | 2025-12-03 | — | — | EP | disclosed |
| WO-2023079291-A1 | DDR1 AND DDR2 INHIBITORS FOR THE TREATEMENT OF CANCER AND FIBROTIC DISEASES | REDX PHARMA PLC (GB) | 2023-05-11 | — | — | WO | disclosed |