Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.38 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.38 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28595233 | 0.86 | MAPT (0.42) | MAPTKDM4EHIF1AHSD17B10ALDH1A1 | |
| SCHEMBL18040333 | 0.83 | KIF11 (0.45) | KDM4EALDH1A1TNFNOD1LMNA | |
| SCHEMBL2602433 | 0.81 | MAPT (0.51) | MAPTKDM4EHIF1AHSD17B10ALDH1A1 | |
| SCHEMBL29903995 | 0.80 | MAPT (0.48) | MAPTKDM4EHIF1AHSD17B10ALDH1A1 | |
| SCHEMBL2605854 | 0.79 | KDM4E (0.52) | MAPTKDM4EHIF1AHSD17B10ALDH1A1 | |
| SCHEMBL28664956 | 0.78 | MAPT (0.56) | MAPTKDM4EHIF1AHSD17B10ALDH1A1 | |
| SCHEMBL29004068 | 0.78 | MAPT (0.51) | MAPTKDM4EHIF1AHSD17B10ALDH1A1 | |
| SCHEMBL29171299 | 0.77 | TDP1 (0.46) | MAPTKDM4EHIF1AHSD17B10ALDH1A1 | |
| SCHEMBL4507676 | 0.77 | POLB (0.45) | MAPTKDM4EHIF1AHSD17B10ALDH1A1 | |
| SCHEMBL19219070 | 0.77 | MAPT (0.46) | MAPTKDM4EHIF1AHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230151270-A1 | Aggregation-Induced Emission Polymer, Preparation Method and Application Thereof | QINGDAO AGRICULTURAL UNIVERSITY (CN) | 2023-05-18 | — | — | US | disclosed |