Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.42 |
| ▸ | CTSG | P08311 | 2/20 | 0.42 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.42 |
| ▸ | CMA1 | P23946 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25477179 | 0.89 | KCNN4 (0.58) | KCNN4PRSS1CTSGCTRB1CMA1 | |
| SCHEMBL25477181 | 0.85 | ALDH1A1 (0.52) | KCNN4ALDH1A1TSHRCES1CYP2C19 | |
| SCHEMBL24781344 | 0.83 | KCNN4 (0.46) | KCNN4ALDH1A1TSHRCES1CYP2C19 | |
| SCHEMBL28983035 | 0.80 | ALDH1A1 (0.47) | KCNN4ALDH1A1TSHRCES1CYP2C19 | |
| SCHEMBL11251 | 0.77 | HTT (0.50) | KCNN4ALDH1A1TSHRCES1CYP2C19 | |
| SCHEMBL888518 | 0.77 | KCNN4 (0.49) | KCNN4CTRB1ALDH1A1TSHRCES1 | |
| SCHEMBL888331 | 0.74 | PIN1 (0.42) | KCNN4ALDH1A1KMT2AMAPTOPRM1 | |
| SCHEMBL818925 | 0.74 | KCNN4 (0.38) | KCNN4ALDH1A1TSHRCES1CYP2C19 | |
| SCHEMBL6368051 | 0.73 | KCNN4 (0.56) | KCNN4PRSS1CTSGCTRB1CMA1 | |
| SCHEMBL6465999 | 0.73 | CA12 (0.41) | KCNN4ALDH1A1TSHRHIF1ACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083295-A1 | ESTER DERIVATIVES OF N4-HYDROXYCYTIDINE AND USE THEREOF | SUZHOU SPRING-SEA BIO-PHARMACEUTICALS CO., LTD. (CN) | 2023-05-19 | — | — | WO | disclosed |