SCHEMBL25477199

SCHEMBL25477199

Cc1ccccc1Oc1ccccc1Cc1cc(C)c(OCC(=O)OC(C)(C)C)c(C)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.38
MTNR1A P48039 2/20 0.37
MTNR1B P49286 2/20 0.37
MAPT P10636 3/20 0.37
TDP1 Q9NUW8 1/20 0.37
ALDH1A1 P00352 2/20 0.37
CYP1A2 P05177 1/20 0.37
HPGD P15428 2/20 0.36
KMT2A Q03164 2/20 0.36
ITGB1 P05556 1/20 0.36
ITGA4 P13612 1/20 0.36
PTPN1 P18031 1/20 0.36
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
TSHR P16473 1/20 0.36
HSD17B10 Q99714 1/20 0.36
SLC6A2 P23975 2/20 0.36
SLC6A4 P31645 2/20 0.36
SLC6A3 Q01959 2/20 0.36
DDB1 Q16531 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25477165 0.86 PTPN1 (0.39) SMN1; SMN2MTNR1AMTNR1BMAPTALDH1A1
SCHEMBL25477154 0.84 PTPN1 (0.42) MTNR1AMTNR1BMAPTALDH1A1HPGD
SCHEMBL7862085 0.77 NOTUM (0.53) SMN1; SMN2MAPTTDP1ALDH1A1CYP1A2
SCHEMBL8958295 0.76 HPGD (0.41) MTNR1AMTNR1BMAPTALDH1A1HPGD
SCHEMBL25629330 0.74 KMT2A (0.41) SMN1; SMN2MAPTALDH1A1HPGDKMT2A
SCHEMBL24908732 0.73 KDM4E (0.47) SMN1; SMN2MAPTTDP1ALDH1A1HPGD
SCHEMBL3683299 0.72 ALDH1A1 (0.41) SMN1; SMN2MAPTTDP1ALDH1A1HPGD
SCHEMBL25477186 0.71 FFAR1 (0.40) SMN1; SMN2MAPTKMT2APTPN1KDM4E
SCHEMBL22656552 0.71 POLB (0.50) SMN1; SMN2MAPTALDH1A1HPGDKMT2A
SCHEMBL21784183 0.71 HPGD (0.42) SMN1; SMN2MTNR1AMTNR1BMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230152697-A1 PHOTORESIST COMPOSITIONS AND PATTERN FORMATION METHODS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2023-05-18 US disclosed